Cholestasis is a condition characterized by the abnormal production or excretion of bile, and
it can be induced by a variety of causes, the factors of which are extremely complex …

Background Primary biliary cholangitis is a rare, chronic cholestatic liver disease
characterized by the destruction of interlobular bile ducts, leading to cholestasis and liver …

The cholangiopathies are a group of liver diseases that affect cholangiocytes, the epithelial
cells that line the bile ducts. Biliary atresia (BA), primary biliary cholangitis (PBC), and …

Background Observational studies have indicated that the incidence of primary biliary
cholangitis (PBC) is higher in inflammatory bowel disease (IBD) patients than that in healthy …

Primary biliary cholangitis (PBC) is an autoimmune liver disease with striking female
predisposition, and selective destruction of intrahepatic small bile ducts leading to non …

Introduction Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease
characterized by the immune-mediated destruction of small and medium intrahepatic bile …

Peripheral helper T cells (Tph) are a specialized subset of CD4+ T cells with the ability to
help B cells and induce antibody production. Although usually located in ectopic lymphoid …

Hirsutella sinensis is the anamorph of Ophiocordyceps sinensis, and its mycelia has been
used to effectively treat a variety of hepatobiliary diseases in clinical practice. In the present …

Cholestatic liver diseases causes inflammation and fibrosis around bile ducts. However, the
pathological mechanism has not been elucidated. Extracellular vesicles (EVs) are released …

Severe diseases like cirrhosis and liver failure can be developed from primary biliary
cholangitis (PBC). Endothelin-2 (EDN2) and endothelin receptor B (EDNRB) are related to …