Chandrasekharappa SC, Teh BT (National Human Genome Research Institute, National
Institutes of Health, Bethesda, MD; and Van Andel Research Institute, Grand Rapids, MI …

Multiple endocrine neoplasia type I (MEN1), a hereditary tumor syndrome, is characterized
by the development of tumors in multiple endocrine organs. The gene mutated in MEN1 …

Parathormone (PTH) and vitamin D are two critical hormonal regulators of calcium
homeostasis. An important cross-talk exists between the PTH and vitamin D hormonal …

Sustained proliferation of cancer cells requires that telomerase maintain chromosomal
stability and prolong telomere length-regulated cell replication. Human telomerase reverse …

The majority of pituitary adenomas occur sporadically, however, about 5% of all cases occur
in a familial setting, of which over half are due to multiple endocrine neoplasia type 1 (MEN …

Multiple endocrine neoplasia type I (MEN1) is a hereditary tumor syndrome characterized by
multiple endocrine and occasionally non-endocrine tumors. The tumor suppressor gene …

Several familial forms of primary hyperparathyroidism (PHTP) have been discovered over
the past 25 years, and molecular test for their risk assessment has been widely increasing …

High levels of blood glucose and lipids are well-known risk factors for heart diseases. Bee
venom is a natural product that has a potent hypoglycemic, hypolipidemic, anti-inflammatory …

Abstract The Multiple Endocrine Neoplasia I (MEN1) locus encodes the protein MENIN,
which functions as a tumor suppressor protein in neuroendocrine tissues. Gastrinomas are …

Pancreatic neuroendocrine tumors (PNETs), which account for 1% to 2% of all pancreatic
neoplasms, are pathologically heterogeneous and consist of epithelial cells with phenotypic …