Pyroptosis is a lytic and inflammatory type of programmed cell death that is usually triggered
by inflammasomes and executed by gasdermin proteins. The main characteristics of …

Inflammasomes are components of the innate immune response that have recently emerged
as crucial controllers of tissue homeostasis. In particular, the nucleotide-binding domain …

Emerging evidence suggests that astrocyte loss is one of the most important pathological
features in the hippocampus of patients with major depressive disorder (MDD) and …

β2 integrins are heterodimeric surface receptors composed of a variable α (CD11a-CD11d)
and a constant β (CD18) subunit and are specifically expressed by leukocytes. The α …

Myocardial ischemia-reperfusion injury (MIRI) results in the aggravation of myocardial injury
caused by rapid recanalization of the ischemic myocardium. In the past few years, there is a …

Pseudomonas aeruginosa is an important opportunistic pathogen responsible for the cause
of acute lung injury and acute respiratory distress syndrome. P. aeruginosa isthe leading …

Intervertebral disc degeneration (IVDD) is a common musculoskeletal degenerative disease
worldwide, of which the main clinical manifestation is low back pain (LBP); approximately …

Cadmium (Cd) and excessive molybdenum (Mo) have adverse impacts on animals.
However, the hepatotoxicity co-induced by Cd and Mo in ducks has not been fully …

Osteoporosis has become a worldwide disease characterized by a reduction in bone
mineral density and the alteration of bone architecture leading to an increased risk of fragility …

Objective Breast cancer is the most common and high-incidence cancer in women. It is
mainly treated by surgery combined with chemoradiation. The main challenge in treating …