Interactions between the immune and nervous systems are of central importance in
neuropathic pain, a common and debilitating form of chronic pain caused by a lesion or …

There is increasing knowledge regarding the role of the microbiome in modulating brain and
behaviour. Indeed, the actions of microbial metabolites are key for appropriate gut-brain …

The gut microbiota has been implicated in chronic pain disorders, including irritable bowel
syndrome (IBS), yet specific pathophysiological mechanisms remain unclear. We showed …

Fibromyalgia Syndrome (FMS) is a disorder of chronic, generalized muscular pain,
accompanied by sleep disturbances, fatigue and cognitive dysfunction. There is no definitive …

From an animal health perspective, relatively little is known about the typical or healthy
ranges of concentrations for many metabolites in bovine biofluids and tissues. Here, we …

This systematic review aims to provide a comprehensive understanding of the current
literature regarding gut microbiota composition in patients with Parkinson's disease (PD) …

Introduction Persistent somatic symptoms (PSS) are highly prevalent in all areas of
medicine; they are disabling for patients and costly for society. The subjective symptom …

Background There is growing evidence of the significance of gastrointestinal complaints in
the impairment of the intestinal mucosal barrier function and inflammation in fibromyalgia …

BACKGROUND: Gut microbiota, a consortium of diverse microorganisms residing in the
gastrointestinal tract, has emerged as a key player in neuroinflammatory responses …

Objective Colorectal cancer (CRC) is the third most diagnosed cancer, and requires surgical
resection and reconnection, or anastomosis, of the remaining bowel to re-establish intestinal …