1 Twenty‐two dialysis dependent patients received an intravenous loading dose of digoxin
of 10 microgram/kg and the mean+/‐sd serum digoxin concentration 24 h later was 1.5 …

The effects of diseases involving the kidney, gastrointestinal tract, thyroid, and
cardiovascular system on the disposition of cardiac glycosides are reviewed. The glycosides …

A compartmental representation of the body is often used to explain the principles of
pharmacokinetics, where the compartments are purely hypothetical and bear no relationship …

The concentrations of digoxin in maternal and foetal serum and in foetal tissues were
measured after two oral doses in 12–16 weeks pregnancies. In maternal serum a digoxin …

Previous dosing schedules for digoxin in renal failure have considered the decrease in the
elimination rate constant but not the decrease in the volume of distribution. A dosing …

Il. Medizinische Klinik und Poliklinik der Universität Mainz (Direktor: Prof. Dr. P. Schölmerich)
die auf einem erhöhten Glykosidgehalt im Organismus beruhen, erkennbar und durch …

Digoxin is effective in controlling ventricular rhythm in atrial fibrillation and is used in heart
failure when angiotensin converting enzyme inhibitors and diuretics are ineffective. Because …

Postmortem tissue and plasma concentrations of digoxin were studied in 13 premature
newborns, 6 mature newborns, and 5 older infants (age 1 to 14 months). The pertinent …

Pharmacology considerations in patients with renal failure have become an area of
increasing importance and expanding knowledge since such patients have been …

The correlation between the daily dose of digoxin, its plasma level and clinical
characteristics of 213 patients receiving β-acetyldigoxin treatment has been evaluated. After …