Potential pre-activation strategies for improving therapeutic efficacy of mesenchymal stem cells: current status and future prospects

M Li, Y Jiang, Q Hou, Y Zhao, L Zhong, X Fu - Stem cell research & …, 2022 - Springer
Mesenchymal stem cell (MSC)-based therapy has been considered as a promising
approach targeting a variety of intractable diseases due to remarkable multiple effect of …

Genetic engineering as a strategy to improve the therapeutic efficacy of mesenchymal stem/stromal cells in regenerative medicine

PKF Damasceno, TSA De Santana… - Frontiers in Cell and …, 2020 - frontiersin.org
Mesenchymal stem/stromal cells (MSCs) have been widely studied in the field of
regenerative medicine for applications in the treatment of several disease settings. The …

[HTML][HTML] Adiponectin stimulates exosome release to enhance mesenchymal stem-cell-driven therapy of heart failure in mice

Y Nakamura, S Kita, Y Tanaka, S Fukuda, Y Obata… - Molecular Therapy, 2020 - cell.com
Mesenchymal stem/stromal cells (MSCs) are cultured adult stem cells that originally reside
in virtually all tissues, and the gain of MSCs by transplantation has become the leading form …

Therapeutic potential and molecular mechanisms of salidroside in ischemic diseases

J Han, L Luo, Y Wang, S Wu, V Kasim - Frontiers in Pharmacology, 2022 - frontiersin.org
Rhodiola is an ancient wild plant that grows in rock areas in high-altitude mountains with a
widespread habitat in Asia, Europe, and America. From empirical belief to research studies …

SDF-1 secreted by mesenchymal stem cells promotes the migration of endothelial progenitor cells via CXCR4/PI3K/AKT pathway

X Wang, H Jiang, L Guo, S Wang, W Cheng… - Journal of molecular …, 2021 - Springer
Cell-based therapeutics bring great hope in areas of unmet medical needs. Mesenchymal
stem cells (MSCs) have been suggested to facilitate neovascularization mainly by paracrine …

Mesenchymal stem cell–based therapy as a new approach for the treatment of systemic sclerosis

X Zhuang, X Hu, S Zhang, X Li, X Yuan… - Clinical reviews in allergy & …, 2022 - Springer
Systemic sclerosis (SSc) is an intractable autoimmune disease with unmet medical needs.
Conventional immunosuppressive therapies have modest efficacy and obvious side effects …

Mesenchymal stem cell transplantation for ischemic diseases: mechanisms and challenges

TT Van Nguyen, NB Vu, P Van Pham - Tissue Engineering and …, 2021 - Springer
Ischemic diseases are conditions associated with the restriction or blockage of blood supply
to specific tissues. These conditions can cause moderate to severe complications in …

Adult stem cell therapy for premature ovarian failure: from bench to bedside

MY Wang, YX Wang, J Li-Ling… - Tissue Engineering Part B …, 2022 - liebertpub.com
Premature ovarian failure (POF) is a devastating condition for women of childbearing age
with serious health consequences, including distress, infertility, osteoporosis, autoimmune …

SIRT5 deficiency enhances the proliferative and therapeutic capacities of adipose‐derived mesenchymal stem cells via metabolic switching

T Ou, W Yang, W Li, Y Lu, Z Dong, H Zhu… - Clinical and …, 2020 - Wiley Online Library
Abstract Background Mesenchymal stem cells (MSCs) have therapeutic potential for multiple
ischemic diseases. However, in vitro expansion of MSCs before clinical application leads to …

Mesenchymal stem cell-mediated mitochondrial transfer: a therapeutic approach for ischemic stroke

M Lu, J Guo, B Wu, Y Zhou, M Wu, M Farzaneh… - Translational Stroke …, 2021 - Springer
Stroke is the leading cause of death and adult disability worldwide. Mitochondrial
dysfunction is one of the hallmarks of stroke-induced neuronal death, and maintaining …