Live attenuated oral polio vaccine (OPV) and inactivated polio vaccine (IPV) are the tools
being used to achieve eradication of wild polio virus. Because OPV can rarely cause …

Introduction: Rapid development and production of vaccines against emerging diseases
requires well established, validated, robust technologies to allow industrial scale production …

Since 2005, a large poliomyelitis outbreak associated with type 2 circulating vaccine-derived
poliovirus (cVDPV2) has occurred in northern Nigeria, where immunization coverage with …

Enterovirus 71 (EV71) was first isolated in 1969 in California, USA. Several epidemic
outbreaks with high mortality rates have occurred in European and Asian Countries …

Implementation of inactivated polio vaccines (IPV) containing Sabin strains (sIPV) will further
enable global polio eradication efforts by improving vaccine safety during use and …

Nearly 20 years after the year 2000 target for global wild poliovirus (WPV) eradication, live
polioviruses continue to circulate with all three serotypes posing challenges for the polio …

Abstract Background The Global Polio Eradication Initiative plans for coordinated cessation
of oral poliovirus vaccine (OPV) after interrupting all wild poliovirus (WPV) transmission, but …

In 2013, the World Health Assembly endorsed a plan that calls for the ultimate withdrawal of
oral polio vaccines (OPV) from all immunization programs globally. The withdrawal would …

Highlights•2012 had the lowest number of polio cases in the lowest number of
countries.•Outbreaks of vaccine-derived poliovirus have increased and are mostly due to …

Introduction: With more than 150 million chronically infected people, hepatitis C virus (HCV)
remains a substantial global health burden. Direct-acting antivirals have dramatically …