Tetherin is an interferon-inducible antiviral protein that inhibits the release of a broad
spectrum of enveloped viruses by retaining virions at the surface of infected cells. While the …

Neuroendocrine tumors of the gastroenteropancreatic system are defined by their endocrine
phenotype and share many histopathological and clinical features. However, the fact that the …

Background Liver metastases are a strong prognostic indicator in patients with gastro-entero-
pancreatic neuroendocrine tumors (GEP-NETs). Therapeutic options for metastatic NETs are …

Neuroendocrine tumors (NET) of the pancreas are uncommon neoplasms that arise from the
pancreatic islet cells. The clinical presentation of specific tumors is characterized by unique …

Exploring the underlying mechanisms of cancer development is useful for cancer treatment.
In this paper, we analyzed the transcriptome profiles from the human normal pancreas …

Background/Aim: Hemostatic system components contribute to cancer progression
independently from their roles in hemostasis. It has been shown that protein Z (PZ)/protein Z …

Although the endocrine component of the pancreas represents about less than 10% of the
volume of the gland, it plays a crucial role in regulating the metabolic functions, mainly the …

The most frequent molecular abnormalities in pancreatic endocrine tumours (PETs) are
mutations of the MEN1 gene, deregulation of the PI3K/AKT/mTOR signalling pathway and …

Purpose Abnormal expression of succinate dehydrogenase,(SDH), in particular of the B
subunit (SDHB), is implicated in the pathogenesis of neuroendocrine tumors. This study …

Bone marrow stromal antigen 2 (BST-2) is a type II membrane protein with two targeting
signals, one of which is located in the cytoplasmic domain and contains a non-canonical …