Phagocytosis and mechanisms of killing of Aspergillus fumigatus conidia by murine alveolar
macrophages (AM), which are the main phagocytic cells of the innate immunity of the lung …

During the past two decades, invasive fungal infections have emerged as a major threat to
immunocompromised hosts. Patients with neoplastic diseases are at significant risk for such …

Inhalation of fungal spores (conidia) occurs commonly and, in specific circumstances, can
result in invasive disease. We investigated the murine inflammatory response to conidia of …

Aspergillus fumigatus is a common cause of invasive and allergic pulmonary disease.
Resting conidia of the filamentous fungus are constantly inhaled, but cause infection only …

Aspergillus fumigatus is a ubiquitous saprophytic mold (67) that forms airborne spores
(conidia). Humans inhale, on average, hundreds of these infectious propagules daily. In …

Microbiological analysis of atmospheres witnessed substantial technical improvements in
the 1940s to 1960s. May's cascade impactor and Hirst's spore trap allowed the counting of …

The immune mechanisms of defence against fungal infections are numerous, and range
from protective mechanisms that were present early in evolution (innate immunity) to …

Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

Aspergillus fumigatus causes a wide range of diseases that include mycotoxicosis, allergic
reactions and systemic diseases (invasive aspergillosis) with high mortality rates …

The evolution of intracellular pathogens is considered in the context of ambiguities in basic
definitions and the diversity of host-microbe interactions. Intracellular pathogenesis is a …