Depression increases the risk of cardiac mortality and morbidity in patients with coronary
heart disease (CHD), but the mechanisms that underlie this association remain unclear. This …

For years, patients with cardiac disease have been thought to exhibit characteristic emo-
tional features. However, the modern understanding of the relationship between affec-tive …

Objective Major depression is a common problem in patients with coronary heart disease
(CHD) and is associated with an increased risk for cardiac morbidity and mortality. It is not …

Depression can be a consequence of medical illness and disability, yet recent literature
suggests it may also influence morbidity and mortality through a variety of behavioral and …

A major factor in the context of evaluating depression in the elderly is the role of medical
problems. With aging there is a rapid increase in the prevalence of a number of medical …

OBJECTIVE: This study compared the efficacy and safety of paroxetine and imipramine with
that of placebo in the treatment of bipolar depression in adult outpatients stabilized on a …

Approximately 20% of patients with coronary heart disease (CHD) have major depression
and 20% have minor depression at any given point in the course of their illness. Depression …

The association between cardiovascular disease and mental depression is multifaceted and
likely bidirectional. Depressed patients are at significantly higher risk for cardiac morbidity …

Background—Identification of factors regulating myocardial structure and function is
important to understand the pathogenesis of heart disease. Because little is known about the …

BACKGROUND: Depression has a complex bidirectional association with heart disease.
Previously we have shown notable cardiovascular changes in the chronic mild stress (CMS) …