Inflammatory bowel disease (IBD), with its major manifestations being Crohn's disease and
ulcerative colitis, belongs to the gastrointestinal inflammatory disorders, whose main …

Emerging evidence suggests that gut-brain-microbiota axis (GBMAx) may play a pivotal role
linking gastrointestinal and neuronal disease. In this review, we summarize the latest …

The gut microbiome has been implicated in the pathogenesis of inflammatory bowel disease
(IBD). Studies suggest that the IBD gut microbiome is less diverse than that of the unaffected …

Diarrhea-predominant irritable bowel syndrome (IBS-D) is one of the most common chronic
functional gastrointestinal diseases with limited treatments. Gut microbiota play an important …

The hypothalamus regulates energy homeostasis by integrating environmental and internal
signals to produce behavioral responses to start or stop eating. Many satiation signals are …

The importance of the gut microbiota in human health is currently well established. It
contributes to many vital functions such as development of the host immune system …

Background Altered intestinal microbiota composition in later life is associated with
inflammaging, declining tissue function, and increased susceptibility to age-associated …

Crohn's disease (CD) and ulcerative colitis (UC) are the two main forms of inflammatory
bowel disease (IBD). Among the various immune cells involved in IBD, neutrophils are the …

Parkinson's disease is characterized by dopaminergic neuron loss and intracellular
inclusions composed mainly of alpha synuclein (α-syn), but the mechanism of pathogenesis …

Altered intestinal microbial composition (dysbiosis) and metabolic products activate
aggressive mucosal immune responses that mediate inflammatory bowel diseases (IBD) …