Capturing the environment of the Clostridioides difficile infection cycle

MK Schnizlein, VB Young - Nature Reviews Gastroenterology & …, 2022 - nature.com
Clostridioides difficile (formerly Clostridium difficile) infection is a substantial health and
economic burden worldwide. Great strides have been made over the past several years in …

Effect of Clostridium butyricum on Gastrointestinal Infections

T Ariyoshi, M Hagihara, M Takahashi, H Mikamo - Biomedicines, 2022 - mdpi.com
Clostridium butyricum is a human commensal bacterium with beneficial effects including
butyrate production, spore formation, increasing levels of beneficial bacteria, and inhibition …

A Pharmacovigilance Study Regarding the Risk of Antibiotic-Associated Clostridioides difficile Infection Based on Reports from the EudraVigilance Database …

BI Vintila, AM Arseniu, C Morgovan, A Butuca, M Sava… - Pharmaceuticals, 2023 - mdpi.com
The Gram-positive anaerobic bacterium Clostridioides difficile (CD) can produce intense
exotoxins, contributing to nosocomial infections, and it is the most common cause of health …

Hypervirulent R20291 Clostridioides difficile spores show disinfection resilience to sodium hypochlorite despite structural changes

D Malyshev, IA Jones, M McKracken, R Öberg… - BMC microbiology, 2023 - Springer
Background Clostridioides difficile is a spore forming bacterial species and the major
causative agent of nosocomial gastrointestinal infections. C. difficile spores are highly …

[HTML][HTML] Clostridioides difficile infection-associated cause-specific and all-cause mortality: a population-based cohort study

A Boven, E Vlieghe, L Engstrand, FL Andersson… - Clinical Microbiology …, 2023 - Elsevier
Objectives Clostridioides difficile infection (CDI) is a common healthcare-associated
infection and leading cause of gastroenteritis-related mortality worldwide. However, data on …

The Environment, Farm Animals and Foods as Sources of Clostridioides difficile Infection in Humans

D Bolton, P Marcos - Foods, 2023 - mdpi.com
The recent discovery of the same Clostridioides difficile ribotypes associated with human
infection in a broad range of environments, animals and foods, coupled with an ever …

The effect of antibiotic therapy for Clostridioides difficile infection on mortality and other patient-relevant outcomes: a systematic review and meta-analysis

Y Stabholz, M Paul - Clinical Microbiology and Infection, 2024 - Elsevier
Background Current practice guidelines favour fidaxomicin over vancomycin and exclude
metronidazole from the recommended standard regimen for Clostridioides difficile infection …

A Real-World Study on the Clinical Characteristics, Outcomes, and Relationship between Antibiotic Exposure and Clostridioides difficile Infection

BI Vintila, AM Arseniu, C Morgovan, A Butuca… - Antibiotics, 2024 - mdpi.com
Clostridioides difficile is a Gram-positive bacteria that causes nosocomial infections,
significantly impacting public health. In the present study, we aimed to describe the clinical …

Immunoinformatics Approach Toward the Introduction of a Novel Multi-Epitope Vaccine Against Clostridium difficile

C Tan, F Zhu, Y Xiao, Y Wu, X Meng, S Liu… - Frontiers in …, 2022 - frontiersin.org
Clostridium difficile (C. difficile) is an exclusively anaerobic, spore-forming, and Gram-
positive pathogen that is the most common cause of nosocomial diarrhea and is becoming …

Epidemiological and clinical burden of Clostridioides difficile infections and recurrences between 2015 − 2019: the RECUR Germany study

A Tricotel, A Antunes, A Wilk, S Dombrowski… - BMC Infectious …, 2024 - Springer
Background This real-world study assessed the epidemiology and clinical complications of
Clostridioides difficile infections (CDIs) and recurrences (rCDIs) in hospital and community …