Lycopene as a natural antioxidant used to prevent human health disorders

M Imran, F Ghorat, I Ul-Haq, H Ur-Rehman, F Aslam… - Antioxidants, 2020 - mdpi.com
Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in
tomato and tomato-based products. It is fundamentally recognized as a potent antioxidant …

Natural products: potential treatments for cisplatin-induced nephrotoxicity

C Fang, D Lou, L Zhou, J Wang, B Yang, Q He… - Acta Pharmacologica …, 2021 - nature.com
Cisplatin is a clinically advanced and highly effective anticancer drug used in the treatment
of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer …

Therapeutic potential of rosmarinic acid: A comprehensive review

M Nadeem, M Imran, T Aslam Gondal, A Imran… - Applied Sciences, 2019 - mdpi.com
Naturally occurring food-derived active ingredients have received huge attention for their
chemopreventive and chemotherapy capabilities in several diseases. Rosmarinic acid (RA) …

Environmentally relevant concentration of sulfamethoxazole-induced oxidative stress-cascaded damages in the intestine of grass carp and the therapeutic application …

Y Wang, H Zhao, Y Liu, J Li, X Nie, P Huang… - Environmental …, 2021 - Elsevier
Due to the unreasonable use and discharge of the aquaculture industry, over standard of the
antibiotics has been frequent in different types of water environments, causing adverse …

Using green biosynthesized lycopene-coated selenium nanoparticles to rescue renal damage in glycerol-induced acute kidney injury in rats

A Al-Brakati, KF Alsharif, KJ Alzahrani… - International journal …, 2021 - Taylor & Francis
Purpose Selenium nanoparticles (SeNPs) have recently gained much attention in
nanomedicine applications owing to their unique biological properties. Biosynthesis of …

The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view

EHM Hassanein, WR Mohamed, OS Ahmed… - Life Sciences, 2022 - Elsevier
Kidney diseases are major health problem and understanding the underlined mechanisms
that lead to kidney diseases are critical research points with a marked potential impact on …

Lycopene triggers nrf2–AMPK cross talk to alleviate atrazine-induced nephrotoxicity in mice

J Lin, J Xia, HS Zhao, R Hou, M Talukder… - Journal of Agricultural …, 2018 - ACS Publications
Atrazine (ATR), an environmental persistent and bioaccumulative herbicide, has been
associated with environmental nephrosis. Lycopene (LYC) exhibits important properties of …

Rosmarinic acid mitigates chlorpyrifos-induced oxidative stress, inflammation, and kidney injury in rats by modulating SIRT1 and Nrf2/HO-1 signaling

MS Abduh, RS Alruhaimi, HA Alqhtani, OE Hussein… - Life Sciences, 2023 - Elsevier
Chlorpyrifos (CPF) is a widely used broad-spectrum pesticide with multi-organ toxic effects.
Oxidative stress was found to play a role in the deleterious effects of CPF, including …

Enhancement of biochemical and genomic pathways through lycopene-loaded nano-liposomes: Alleviating insulin resistance, hepatic steatosis, and autophagy in …

GA Salem, AAR Mohamed, SI Khater, AE Noreldin… - Gene, 2023 - Elsevier
Non-alcoholic fatty liver (NAFL) is a prevalent hepatic disorder of global significance that can
give rise to severe complications. This research endeavor delves into the potential of nano …

Acute and Subacute Toxicity Profiles of the Methanol Extract of Lycopersicon esculentum L. Leaves (Tomato), a Botanical with Promising In Vitro Anticancer Potential

GS Nguenang, ASM Ntyam… - … and Alternative Medicine, 2020 - Wiley Online Library
Lycopersicon esculentum (tomato) is a plant widely used in Africa like food and to solve
many health problems. The methanol crude extract of tomato recently demonstrated a good …