Rapid determination of triglyceride and glucose levels in Drosophila melanogaster induced by high-sugar or high-fat diets based on near-infrared spectroscopy

J Huang, P Wang, Y Wu, L Zeng, X Ji, X Zhang, M Wu… - Heliyon, 2023 - cell.com
Triglyceride and glucose levels are important indicators for determining metabolic
syndrome, one of the leading public-health burdens worldwide. Drosophila melanogaster is …

Dietary alpha-ketoglutarate promotes higher protein and lower triacylglyceride levels and induces oxidative stress in larvae and young adults but not in middle-aged …

MM Bayliak, MP Lylyk, HV Shmihel… - … and Physiology Part A …, 2017 - Elsevier
Alpha-ketoglutarate (AKG) is involved in multiple metabolic and regulatory pathways. In this
work, the effects of AKG-supplemented diets on selected physiological responses and …

Lipid quantity and composition vary between three European house fly strains

F Boatta, WL Jansen, LW Beukeboom… - Entomologia …, 2023 - Wiley Online Library
Lipids are an important class of nutrients for insects, as they are the main energy source
during metamorphosis and crucial for survival and reproduction. Lipid reserves in insects …

[HTML][HTML] Modeling dietary influences on offspring metabolic programming in Drosophila melanogaster

RT Brookheart, JG Duncan - Reproduction (Cambridge, England), 2016 - ncbi.nlm.nih.gov
The influence of nutrition on offspring metabolism has become a hot topic in recent years
owing to the growing prevalence of maternal and childhood obesity. Studies in mammals …

5-Hydroxymethylfurfural mediated developmental toxicity in Drosophila melanogaster

X Chen, Q Tu, W Zhao, X Lin, Z Chen, B Li… - Food and Chemical …, 2024 - Elsevier
hydroxymethylfurfural is a common byproduct in food. However, its effect on growth and
development remains incompletely understood. This study investigated the developmental …

Inositol in Disease and Development: Roles of Catabolism via myo-Inositol Oxygenase in Drosophila melanogaster

A Contreras, MK Jones, ED Eldon, LS Klig - International Journal of …, 2023 - mdpi.com
Inositol depletion has been associated with diabetes and related complications. Increased
inositol catabolism, via myo-inositol oxygenase (MIOX), has been implicated in decreased …

Activation of the Tor/Myc signaling axis in intestinal stem and progenitor cells affects longevity, stress resistance and metabolism in Drosophila

OM Strilbytska, UV Semaniuk, KB Storey… - … and Physiology Part B …, 2017 - Elsevier
The TOR (target of rapamycin) signaling pathway and the transcriptional factor Myc play
important roles in growth control. Myc acts, in part, as a downstream target of TOR to …

Solanum anguivi Lam. fruit preparations counteract the negative effects of a high-sugar diet on the glucose metabolism in Drosophila melanogaster

AMS Nakitto, S Rudloff, C Borsch, AE Wagner - Food & Function, 2021 - pubs.rsc.org
Solanum anguivi Lam. fruits (SALF) are traditionally consumed as a remedy for type 2
diabetes mellitus (T2DM). However, data regarding the potential anti-diabetic effect of SALF …

A functional analysis of the Purine Salvage Pathway in Acetobacter fabarum

PD Newell, LM Preciado, CG Murphy Jr - Journal of Bacteriology, 2022 - Am Soc Microbiol
Acetobacter species are a major component of the gut microbiome of the fruit fly Drosophila
melanogaster, a widely used model organism. While a range of studies have illuminated …

Changing ROS, NAD and AMP: A path to longevity via mitochondrial therapeutics

O Lushchak, D Gospodaryov, O Strilbytska… - Advances in Protein …, 2023 - Elsevier
Lifespan of many organisms, from unicellular yeast to extremely complex human organism,
strongly depends on the genetic background and environmental factors. Being among most …