Physical exercise for Parkinson's disease: Clinical and experimental evidence

A Oliveira de Carvalho… - Clinical Practice and …, 2018 - benthamopen.com
Background: National projections about the increase in the elderly population over 60 years
bring with it an increase in the number of people affected by Parkinson's Disease (PD) …

[HTML][HTML] Physical exercise for Parkinson's disease: clinical and experimental evidence

AO de Carvalho, AS Sá Filho… - Clinical practice and …, 2018 - ncbi.nlm.nih.gov
Background: National projections about the increase in the elderly population over 60 years
bring with it an increase in the number of people affected by Parkinson's Disease (PD) …

Validation of the non-motor symptoms questionnaire (NMS-Quest)

SR Romenets, C Wolfson, C Galatas, A Pelletier… - Parkinsonism & related …, 2012 - Elsevier
BACKGROUND: Although non-motor manifestations of Parkinson's disease are common
and can cause severe disability, they are often under-recognized, leading to missed …

Genetic mouse models of Parkinson's disease: the state of the art

I Magen, MF Chesselet - Progress in brain research, 2010 - Elsevier
The identification of several mutations causing familial forms of Parkinson's disease (PD)
has led to the creation of multiple lines of mice expressing similar genetic alterations. These …

Drug development in Parkinson's disease: from emerging molecules to innovative drug delivery systems

E Garbayo, E Ansorena, MJ Blanco-Prieto - Maturitas, 2013 - Elsevier
Current treatments for Parkinson's disease (PD) are aimed at addressing motor symptoms
but there is no therapy focused on modifying the course of the disease. Successful treatment …

[HTML][HTML] Apathy as a behavioural marker of cognitive impairment in Parkinson's disease: a longitudinal analysis

GP Martin, KR McDonald, D Allsop, PJ Diggle… - Journal of neurology, 2020 - Springer
Background Understanding the longitudinal course of non-motor symptoms, and finding
markers to predict cognitive decline in Parkinson's disease (PD), are priorities. Previous …

Disability and profiles of functioning of patients with Parkinson's disease described with ICF classification

A Raggi, M Leonardi, D Ajovalasit… - International Journal …, 2011 - journals.lww.com
The objective of this study was to describe the functional profiles of patients with Parkinson's
disease (PD), and the relationships between impairment in body functions, limitations in …

[HTML][HTML] Conditional deletion of Ndufs4 in dopaminergic neurons promotes Parkinson's disease-like non-motor symptoms without loss of dopamine neurons

WS Choi, HW Kim, F Tronche, RD Palmiter, DR Storm… - Scientific reports, 2017 - nature.com
Reduction of mitochondrial complex I activity is one of the major hypotheses for
dopaminergic neuron death in Parkinson's disease. However, reduction of complex I activity …

Carboxymethyl chitosan dopamine conjugates: Synthesis and evaluation for intranasal anti Parkinson therapy

S Di Gioia, G Fracchiolla, S Cometa, FM Perna… - International Journal of …, 2023 - Elsevier
With respect to the Parkinson's disease (PD), herein, we aimed at synthetizing and
characterizing two novel macromolecular conjugates where dopamine (DA) was linked to N …

Abdominal massage for the relief of constipation in people with Parkinson's: a qualitative study

D McClurg, K Walker, P Aitchison… - Parkinson's …, 2016 - Wiley Online Library
Objectives. To explore the experiences of people with Parkinson's (PwP) who suffer from
constipation, the impact this has on their lives, and the effect of using lifestyle changes and …