Inflammaging and 'Garb-aging'

C Franceschi, P Garagnani, G Vitale, M Capri… - Trends in Endocrinology …, 2017 - cell.com
'Inflammaging'refers to the chronic, low-grade inflammation that characterizes aging.
Inflammaging is macrophage centered, involves several tissues and organs, including the …

Diagnosing antiphospholipid syndrome:'extra-criteria'manifestations and technical advances

S Sciascia, MC Amigo, D Roccatello… - Nature Reviews …, 2017 - nature.com
First described in the early 1980s, antiphospholipid syndrome (APS) is a unique form of
acquired autoimmune thrombophilia in which patients present with clinical features of …

[HTML][HTML] Pathophysiological bases of comorbidity in migraine

C Altamura, I Corbelli, M De Tommaso… - Frontiers in human …, 2021 - frontiersin.org
Despite that it is commonly accepted that migraine is a disorder of the nervous system with a
prominent genetic basis, it is comorbid with a plethora of medical conditions. Several studies …

Smoke and autoimmunity: The fire behind the disease

C Perricone, M Versini, D Ben-Ami, S Gertel… - Autoimmunity …, 2016 - Elsevier
The association between smoke habit and autoimmunity has been hypothesized a long time
ago. Smoke has been found to play a pathogenic role in certain autoimmune disease as it …

Guidelines for biomarkers in autoimmune rheumatic diseases-evidence based analysis

R Giacomelli, A Afeltra, A Alunno, E Bartoloni-Bocci… - Autoimmunity …, 2019 - Elsevier
Autoimmune rheumatic diseases are characterised by an abnormal immune system
response, complement activation, cytokines dysregulation and inflammation. In last years …

Obstetric and vascular antiphospholipid syndrome: same antibodies but different diseases?

PL Meroni, MO Borghi, C Grossi… - Nature Reviews …, 2018 - nature.com
Recurrent thrombosis and miscarriages are the main clinical manifestations of
antiphospholipid syndrome (APS). Although most patients display both clinical signs, some …

The antiphospholipid syndrome: from pathophysiology to treatment

S Negrini, F Pappalardo, G Murdaca, F Indiveri… - Clinical and …, 2017 - Springer
Antiphospholipid antibody syndrome (APS) is an autoimmune acquired thrombophilia
characterized by recurrent thrombosis and pregnancy morbidity in the presence of …

[HTML][HTML] Antiphospholipid antibody assays in 2021: looking for a predictive value in addition to a diagnostic one

PL Meroni, MO Borghi - Frontiers in immunology, 2021 - frontiersin.org
Antiphospholipid antibodies (aPL) are mandatory for the diagnosis but are also a risk factor
for the antiphospholipid syndrome (APS) clinical manifestations. Lupus anticoagulant (LA) …

[HTML][HTML] Management of antiphospholipid syndrome

A Ghembaza, D Saadoun - Biomedicines, 2020 - mdpi.com
Antiphospholipid syndrome (APS), is an acquired autoimmune disorder characterised by
thrombosis, pregnancy morbidity, and the presence of antiphospholipid antibodies (aPL) …

[HTML][HTML] Immunological tolerance, pregnancy, and preeclampsia: the roles of semen microbes and the father

LC Kenny, DB Kell - Frontiers in medicine, 2018 - frontiersin.org
Although it is widely considered, in many cases, to involve two separable stages (poor
placentation followed by oxidative stress/inflammation), the precise originating causes of …