Effects of caffeine on intracranial pressure and pain perception in freely moving rats
IME Israelsen, CSJ Westgate… - … : The Journal of …, 2023 - Wiley Online Library
Objective Caffeine, a non‐selective adenosine receptor (AR) antagonist, is the most
consumed psychostimulant in the world. Caffeine has been suggested to regulate …
consumed psychostimulant in the world. Caffeine has been suggested to regulate …
Metabotropic glutamate mGlu5 receptor-mediated modulation of the ventral striopallidal GABA pathway in rats. Interactions with adenosine A2A and dopamine D2 …
Interactions between subtypes of dopamine, glutamate and adenosine receptors seem to
play an important integrative role in the function of striatal gamma-aminobutyric acid (GABA) …
play an important integrative role in the function of striatal gamma-aminobutyric acid (GABA) …
Adenosine and related drugs in brain diseases: present and future in clinical trials
LV Lopes, AM Sebastiao… - Current topics in …, 2011 - ingentaconnect.com
Adenosine is a naturally occurring nucleoside present ubiquitously throughout the body as a
metabolic intermediate. Besides its metabolic role within the cells, adenosine is released …
metabolic intermediate. Besides its metabolic role within the cells, adenosine is released …
Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum
K Chergui, P Svenningsson… - Proceedings of the …, 2004 - National Acad Sciences
Dopaminergic and glutamatergic neurotransmissions in the striatum play an essential role in
motor-and reward-related behaviors. Dysfunction of these neurotransmitter systems has …
motor-and reward-related behaviors. Dysfunction of these neurotransmitter systems has …
Structurally Enabled Discovery of Adenosine A2A Receptor Antagonists
A Jazayeri, SP Andrews, FH Marshall - Chemical reviews, 2017 - ACS Publications
Over the past decade there has been a revolution in the field of G protein-coupled receptor
(GPCR) structural biology. Many years of innovative research from different areas have …
(GPCR) structural biology. Many years of innovative research from different areas have …
Reciprocal interactions between adenosine A2A and dopamine D2 receptors in Chinese hamster ovary cells co-transfected with the two receptors
B Kull, S Ferré, G Arslan, P Svenningsson… - Biochemical …, 1999 - Elsevier
Human adenosine A2A and rat dopamine D2 receptors (A2A and D2 receptors) were co-
transfected in Chinese hamster ovary (CHO) cells to study the interactions between two …
transfected in Chinese hamster ovary (CHO) cells to study the interactions between two …
Adenosine/dopamine interaction: implications for the treatment of Parkinson's disease
Evidence for a role of dopaminergic neurotransmission in the motor effects of adenosine
antagonists, such as caffeine, is reviewed, based on the existence of specific antagonistic …
antagonists, such as caffeine, is reviewed, based on the existence of specific antagonistic …
Decreased striatal levels of PEP-19 following MPTP lesion in the mouse
PEP-19 is a neuronal calmodulin-binding protein, and as such, a putative modulator of
calcium regulated processes. In the present study, we used proteomics technology …
calcium regulated processes. In the present study, we used proteomics technology …
Evidence for functional adenosine A3 receptors in microglia cells
C Hammarberg, G Schulte… - Journal of …, 2003 - Wiley Online Library
Adenosine exerts its effects through four subtypes of G‐protein‐coupled receptors (GPCRs):
adenosine A1 and A3 receptors (A3R), which generally couple to Gi proteins and adenosine …
adenosine A1 and A3 receptors (A3R), which generally couple to Gi proteins and adenosine …
Adenosine–dopamine interactions: development of a concept and some comments on therapeutic possibilities
BB Fredholm, P Svenningsson - Neurology, 2003 - AAN Enterprises
This brief review presents a personal perspective on the historical development of the
current knowledge about the biologically important concept of functional antagonism …
current knowledge about the biologically important concept of functional antagonism …