Adenosine plays a key role in the regulation of tissue oxygenation, neuronal firing, and
neurotransmitter release. Four receptor subtypes have been identified and cloned: A 1, A …

Changes on 5-HT2 receptor mRNAs in striatum and subthalamic nucleus in Parkinson's
disease model. PHYSIOL. BEHAV. 00 (0), 000-000, 2006. Abnormal interactions between …

The adenosine A2A receptor (ADORA2A) is linked to the dopamine neurotransmitter system
and is also implicated in the regulation of alertness, suggesting a potential association with …

Estrogen (E) treatment of ovariectomized animals increases dendritic spines and/or synaptic
protein expression in the hippocampus of female rats [J Neurosci 12 (1992) 2549; …

The extensive role of adenosine in discriminating input from the extracellular environment is
effected through a series of cell membrane-spanning proteins–the adenosine A 1, A 2A, A …

Behavioral activation is regulated by dopamine (DA) in striatal areas. At low doses, while
typical antipsychotic drugs produce psychomotor slowing, psychostimulants promote …

Abstract Autism Spectrum Disorders (ASD) are neurodevelopmental disorders whose
diagnosis relies on deficient social interaction and communication together with repetitive …

Key points Adenosine is a widespread neuromodulator in the mammalian brain, but whether
it affects information processing in sensory system (s) remains largely unknown. Here we …

Introduction: Caffeine and the selective A2A receptor antagonist SCH58261 both have
ergogenic properties, effectively reducing fatigue and enhancing exercise capacity. This …

In this study thirteen 2-aminopyrimidine derivatives were synthesised and screened as
potential antagonists of adenosine A 1 and A 2A receptors in order to further investigate the …