G protein-coupled receptors (GPCRs) undergo ligand-induced internalization that carries
the cognate ligands into intracellular compartments. The present study explores this property …

Many tests are used to determine the toxic activity of miscellaneous substances, and those
that are simple, fast, and inexpensive are useful for screening compounds with applications …

Cancer is the leading cause of death and the most significant determinant of life expectancy
in almost every country in this twenty-first century. According to the World Health …

Objective: This study aimed to prepare combretastatin A4 (CA4)-loaded nanoparticles (CA4
NPs) using poly (lactic-co-glycolic acid)(PLGA) and soybean lecithin (Lipoid S100) as …

The antitumor macrolide aplyronine A (ApA) disturbs microtubule (MT) dynamics by inducing
the protein–protein interaction (PPI) between actin and tubulin. However, the detailed …

Nanomaterials are promising platforms for cancer therapy due to their innate passive
targeting. The success of nanomaterials into the clinics depends on their blood circulation …

STK405759 as a combination therapy with bortezomib or dexamethasone, in in vitro and in
vivo multiple myeloma models - PMC Back to Top Skip to main content NIH NLM Logo Access …

The current perspectives on the nanoparticle have proved that it plays a promising role in
the field of nanomedicine. The basic understanding of nanoparticle action in the biological …

Les cancers du sein triple négatifs, un sous-type de cancer du sein présentant un déficit de
trois récepteurs communément utilisés en thérapie, représentent un important défi …

O câncer de pulmão é uma das maiores causas de morte no mundo, sendo responsável por
aproximadamente 2, 1 milhões de novos casos ao ano. No Brasil, é o quarto tipo de câncer …