Periodontitis and rheumatoid arthritis: What have we learned about their connection and their treatment?

J González‐Febles, M Sanz - Periodontology 2000, 2021 - Wiley Online Library
Rheumatoid arthritis and periodontitis are chronic inflammatory diseases defined
respectively by the destruction of the articular cartilage and tooth‐supporting periodontal …

Oral inflammation and infection, and chronic medical diseases: implications for the elderly

FA Scannapieco, A Cantos - Periodontology 2000, 2016 - Wiley Online Library
Oral diseases, such as caries and periodontitis, not only have local effects on the dentition
and on tooth‐supporting tissues but also may impact a number of systemic conditions …

Host–microbiota interactions in rheumatoid arthritis

Y Maeda, K Takeda - Experimental & Molecular Medicine, 2019 - nature.com
The gut microbiota has been proposed to be an important environmental factor in the
development of rheumatoid arthritis (RA). Here, we review a growing body of evidence from …

Linkage of periodontitis and rheumatoid arthritis: current evidence and potential biological interactions

RS de Molon, C Rossa Jr, RM Thurlings… - International journal of …, 2019 - mdpi.com
The association between rheumatoid arthritis (RA) and periodontal disease (PD) has been
the focus of numerous investigations driven by their common pathological features. RA is an …

Citrullination and autoimmunity

G Valesini, MC Gerardi, C Iannuccelli, VA Pacucci… - Mosaic of …, 2019 - Elsevier
Autoimmune diseases are characterized by the body's own immune system attack to the self-
tissues, a condition enabled, in predisposed subjects, by the reduction of self-tolerance. A …

Role of gut microbiota in rheumatoid arthritis

Y Maeda, K Takeda - Journal of clinical medicine, 2017 - mdpi.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease, caused by both genetic and
environmental factors. Recently, investigators have focused on the gut microbiota, which is …

The link between periodontal disease and rheumatoid arthritis: an updated review

J Koziel, P Mydel, J Potempa - Current rheumatology reports, 2014 - Springer
Porphyromonas gingivalis is a leading pathogen in chronic periodontitis, a disease process
involving progressive destruction of the tissues that support the teeth. Recently, the …

Antibodies to Porphyromonas gingivalis Indicate Interaction Between Oral Infection, Smoking, and Risk Genes in Rheumatoid Arthritis Etiology

N Kharlamova, X Jiang, N Sherina… - Arthritis & …, 2016 - Wiley Online Library
Objective To investigate the role of the periodontal pathogen Porphyromonas gingivalis in
the etiology of rheumatoid arthritis (RA) by analyzing the antibody response to the P …

Diagnosis and classification of rheumatoid arthritis

M Kourilovitch, C Galarza-Maldonado… - Journal of …, 2014 - Elsevier
Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease of unclear etiology that
is manifested in by a progressive and destructive polyarthritis in association with serological …

Mechanisms involved in triggering rheumatoid arthritis

AI Catrina, V Joshua, L Klareskog… - Immunological …, 2016 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic inflammatory syndrome with a strong autoimmune
component. The autoantigens in RA are neither tissue nor organ‐specific, but comprise a …