Transplanting neural progenitor cells to restore connectivity after spinal cord injury

I Fischer, JN Dulin, MA Lane - Nature Reviews Neuroscience, 2020 - nature.com
Spinal cord injury remains a scientific and therapeutic challenge with great cost to
individuals and society. The goal of research in this field is to find a means of restoring lost …

[PDF][PDF] Autonomic consequences of spinal cord injury

S Hou, AG Rabchevsky - Compr Physiol, 2014 - researchgate.net
Spinal cord injury (SCI) results not only in motor and sensory deficits but also in autonomic
dysfunctions. The disruption of connections between higher brain centers and the spinal …

Plasticity in reflex pathways to the lower urinary tract following spinal cord injury

WC de Groat, N Yoshimura - Experimental neurology, 2012 - Elsevier
The lower urinary tract has two main functions, storage and periodic expulsion of urine, that
are regulated by a complex neural control system in the brain and lumbosacral spinal cord …

Spinal circuitry and respiratory recovery following spinal cord injury

MA Lane, KZ Lee, DD Fuller, PJ Reier - Respiratory physiology & …, 2009 - Elsevier
Numerous studies have demonstrated anatomical and functional neuroplasticity following
spinal cord injury. One of the more notable examples is return of ipsilateral phrenic …

Partners in crime: NGF and BDNF in visceral dysfunction

A Coelho, R Oliveira, T Antunes-Lopes… - Current …, 2019 - ingentaconnect.com
Neurotrophins (NTs), particularly Nerve Growth Factor (NGF) and Brain-Derived
Neurotrophic Factor (BDNF), have attracted increasing attention in the context of visceral …

Enhanced susceptibility to urinary tract infection in the spinal cord-injured host with neurogenic bladder

ZR Balsara, SS Ross, PC Dolber, JS Wiener… - Infection and …, 2013 - Am Soc Microbiol
Neurogenic bladder predisposes to recurrent urinary tract infections (UTI) and renal failure,
and susceptibility is commonly ascribed to urinary stasis from elevated residual urine …

Pre-phrenic interneurons: characterization and role in phrenic pattern formation and respiratory recovery following spinal cord injury

MGZ Ghali, G Britz, KZ Lee - Respiratory Physiology & Neurobiology, 2019 - Elsevier
The phrenic motor system receives excitatory inspiratory bulbospinal drive from inspiratory
pre-motor neurons in the rostral ventral respiratory group and descending inhibition from …

Dopamine is produced in the rat spinal cord and regulates micturition reflex after spinal cord injury

S Hou, DM Carson, D Wu, MC Klaw, JD Houlé… - Experimental …, 2016 - Elsevier
Dopamine (DA) neurons in the mammalian central nervous system are thought to be
restricted to the brain. DA-mediated regulation of urinary activity is considered to occur …

Sacral neuromodulation for lower urinary tract dysfunction and impact on erectile function

G Lombardi, N Mondaini, G Giubilei… - The journal of sexual …, 2008 - academic.oup.com
Introduction The first sacral nerve stimulators were for urinary urgency incontinence, urgency‐
frequency, and nonobstructive urinary retention. Since then, observations have been made …

Sprouting of CGRP primary afferents in lumbosacral spinal cord precedes emergence of bladder activity after spinal injury

NDT Zinck, VF Rafuse, JW Downie - Experimental neurology, 2007 - Elsevier
Spinal cord injury (SCI) severely disrupts bladder function. What mediates bladder
dysfunction after SCI is currently unknown. We investigated the role that primary afferent …