I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Chronic rhinosinusitis (CRS) is a common clinical syndrome that produces significant
morbidity and costs to our health system. The study of CRS has progressed from an era …

Chronic rhinosinusitis (CRS) affects up to 12% of the general population and is traditionally
divided into two main phenotypic subsets, based on the presence of nasal polyps …

Objectives Nasal polyps are often characterized by type 2 inflammation and disease
recurrence. We developed a new surgical technique, referred to as reboot approach, which …

Chronic rhinosinusitis (CRS) is an inflammatory disease of the sinonasal mucosa. It is likely
due to a dysregulated immune response directed against, and also modified by, antigens …

It is increasingly recognized that chronic rhinosinusitis (CRS) comprises a spectrum of
different diseases with distinct clinical presentations and pathogenic mechanisms. Defining …

Chronic rhinosinusitis (CRS) is a prevalent and heterogeneous disease associated with a
high degree of morbidity. Although there exist specific conditions for diagnosis, it has been …

Objective: The large amount of evidence and the renewed interest in upper and lower
airways involvement in infectious and inflammatory diseases has led Interasma (Global …

Rationale: Chronic obstructive pulmonary disease (COPD) exacerbations are a major cause
of morbidity and mortality, and preventing them is a key treatment target. Long-term …

The novel antibiotic-exploiting strategy in the treatment of Alzheimer's (AD) and Parkinson's
(PD) disease has emerged as a potential breakthrough in the field. The research in animal …