New and emerging approaches to treat psychiatric disorders
Psychiatric disorders are highly prevalent, often devastating diseases that negatively impact
the lives of millions of people worldwide. Although their etiological and diagnostic …
the lives of millions of people worldwide. Although their etiological and diagnostic …
[HTML][HTML] The potential role of gut microbiota in Alzheimer's disease: from diagnosis to treatment
A Varesi, E Pierella, M Romeo, GB Piccini, C Alfano… - Nutrients, 2022 - mdpi.com
Gut microbiota is emerging as a key regulator of many disease conditions and its
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …
[HTML][HTML] The neurochemistry of autism
R Marotta, MC Risoleo, G Messina, L Parisi… - Brain sciences, 2020 - mdpi.com
Autism spectrum disorder (ASD) refers to complex neurobehavioral and
neurodevelopmental conditions characterized by impaired social interaction and …
neurodevelopmental conditions characterized by impaired social interaction and …
[HTML][HTML] Linked dimensions of psychopathology and connectivity in functional brain networks
Neurobiological abnormalities associated with psychiatric disorders do not map well to
existing diagnostic categories. High co-morbidity suggests dimensional circuit-level …
existing diagnostic categories. High co-morbidity suggests dimensional circuit-level …
Brain disorders? precisely
TR Insel, BN Cuthbert - Science, 2015 - science.org
Mental disorders represent a public health challenge of staggering proportions. In the most
recent Global Burden of Disease study, mental and substance abuse disorders constitute …
recent Global Burden of Disease study, mental and substance abuse disorders constitute …
Evaluation of the social motivation hypothesis of autism: a systematic review and meta-analysis
Importance The social motivation hypothesis posits that individuals with autism spectrum
disorder (ASD) find social stimuli less rewarding than do people with neurotypical activity …
disorder (ASD) find social stimuli less rewarding than do people with neurotypical activity …
A dopamine hypothesis of autism spectrum disorder
D Pavăl - Developmental neuroscience, 2017 - karger.com
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. While several theories have …
characterized by social deficits and stereotyped behaviors. While several theories have …
Rhythm and timing as vulnerabilities in neurodevelopmental disorders
Millions of children are impacted by neurodevelopmental disorders (NDDs), which unfold
early in life, have varying genetic etiologies and can involve a variety of specific or …
early in life, have varying genetic etiologies and can involve a variety of specific or …
Mechanisms of dopamine transporter regulation in normal and disease states
RA Vaughan, JD Foster - Trends in pharmacological sciences, 2013 - cell.com
The dopamine (DA) transporter (DAT) controls the spatial and temporal dynamics of DA
neurotransmission by driving reuptake of extracellular transmitter into presynaptic neurons …
neurotransmission by driving reuptake of extracellular transmitter into presynaptic neurons …
Enteric short-chain fatty acids: microbial messengers of metabolism, mitochondria, and mind: implications in autism spectrum disorders
DF MacFabe - Microbial ecology in health and disease, 2015 - Taylor & Francis
Clinical observations suggest that gut and dietary factors transiently worsen and, in some
cases, appear to improve behavioral symptoms in a subset of persons with autism spectrum …
cases, appear to improve behavioral symptoms in a subset of persons with autism spectrum …