Psychiatric disorders are highly prevalent, often devastating diseases that negatively impact
the lives of millions of people worldwide. Although their etiological and diagnostic …

Gut microbiota is emerging as a key regulator of many disease conditions and its
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …

Autism spectrum disorder (ASD) refers to complex neurobehavioral and
neurodevelopmental conditions characterized by impaired social interaction and …

Neurobiological abnormalities associated with psychiatric disorders do not map well to
existing diagnostic categories. High co-morbidity suggests dimensional circuit-level …

Mental disorders represent a public health challenge of staggering proportions. In the most
recent Global Burden of Disease study, mental and substance abuse disorders constitute …

Importance The social motivation hypothesis posits that individuals with autism spectrum
disorder (ASD) find social stimuli less rewarding than do people with neurotypical activity …

Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by social deficits and stereotyped behaviors. While several theories have …

Millions of children are impacted by neurodevelopmental disorders (NDDs), which unfold
early in life, have varying genetic etiologies and can involve a variety of specific or …

The dopamine (DA) transporter (DAT) controls the spatial and temporal dynamics of DA
neurotransmission by driving reuptake of extracellular transmitter into presynaptic neurons …

Clinical observations suggest that gut and dietary factors transiently worsen and, in some
cases, appear to improve behavioral symptoms in a subset of persons with autism spectrum …