Effective innate immune response in natural HIV-1 controller... : Current Opinion in HIV and
AIDS Effective innate immune response in natural HIV-1 controllers. Can mimicking lead to …

Antigen-specific stem-like memory CD8+ T cells (Tscm) have a series of stem cell
characteristics, including long-term survival, self-renewal, anti-apoptosis and persistent …

Abstract Purpose of Review Recent findings on the critical pathogenic role of type 1
interferons (IFN-I) in HIV-1 persistence in humanized mice suggest that inhibiting IFN-I …

Humanized mice for studying HIV latency and potentially its... : Current Opinion in HIV and
AIDS Humanized mice for studying HIV latency and potentially its eradication : Current …

HIV-1 infection can be controlled by anti-retroviral drug therapy, but this is a lifetime
treatment and the virus remains latent and rapidly rebounds if therapy is stopped. HIV-1 …

Mice reconstituted with a human immune system (humanized mice) provide a robust model
to study human immunology, vaccinology, and human infectious diseases. However, the …

Background Although cell surface immune checkpoint proteins (ICPs) such as PD-1
expressed on T cells are associated with T-cell exhaustion, HIV disease progression, and …

Common approaches for monitoring T cell responses are limited in their multiplexity and
sensitivity. In contrast, deep sequencing of the T Cell Receptor (TCR) repertoire provides a …

Mast cells (MCs) distribute to interface tissues with environment, such as skin, airway, and
gut mucosa, thereby functioning as the sentinel against invading allergens and pathogens …

TLR agonists are a promising class of immune system stimulants investigated for
immunomodulatory applications in cancer immunotherapy and viral diseases. In this study …