Channelopathy-causing mutations in the S45A/S45B and HA/HB helices of KCa2. 3 and KCa3. 1 channels alter their apparent Ca2+ sensitivity

R Orfali, YW Nam, HM Nguyen, MA Rahman, G Yang… - Cell Calcium, 2022 - Elsevier
Small-and intermediate-conductance Ca 2+-activated potassium (K Ca 2. x and K Ca 3.1,
also called SK and IK) channels are activated exclusively by a Ca 2+-calmodulin gating …

[HTML][HTML] A computational model of pig ventricular cardiomyocyte electrophysiology and calcium handling: Translation from pig to human electrophysiology

N Gaur, XY Qi, D Benoist, O Bernus… - PLoS computational …, 2021 - journals.plos.org
The pig is commonly used as an experimental model of human heart disease, including for
the study of mechanisms of arrhythmia. However, there exist differences between human …

Genetic Mutations of KCa2. 3 and KCa3. 1 Channels Affect Ca2+ Sensitivity

RS Orfali - 2023 - search.proquest.com
The Ca 2+-activated potassium channels K Ca channels are a unique family of potassium
channels activated by intracellular calcium. K Ca channels are critical for maintaining K+ …

Genetic Mutations of KCa2.3 and KCa3.1 Channels Affect Ca2+ Sensitivity

R Orfali - 2023 - digitalcommons.chapman.edu
The Ca 2+-activated potassium channels K Ca channels are a unique family of potassium
channels activated by intracellular calcium. K Ca channels are critical for maintaining K+ …