Occupational noise exposure: A review of its effects, epidemiology, and impact with recommendations for reducing its burden

CL Themann, EA Masterson - The Journal of the acoustical society of …, 2019 - pubs.aip.org
Exposure to hazardous noise is one of the most common occupational risks, both in the US
and worldwide. Repeated overexposure to noise at or above 85 dBA can cause permanent …

Current insights in noise-induced hearing loss: a literature review of the underlying mechanism, pathophysiology, asymmetry, and management options

TN Le, LV Straatman, J Lea… - … of Otolaryngology-Head …, 2017 - journals.sagepub.com
Background Noise-induced hearing loss is one of the most common forms of sensorineural
hearing loss, is a major health problem, is largely preventable and is probably more …

[HTML][HTML] Diabetes mellitus and hearing loss: a review

D Samocha-Bonet, B Wu, DK Ryugo - Ageing Research Reviews, 2021 - Elsevier
Diabetes (type 2) and sensorineural hearing loss are common health problems manifested
with ageing. While both type 1 and type 2 diabetes have been associated with hearing loss …

Targeting dysregulation of redox homeostasis in noise-induced hearing loss: oxidative stress and ROS signaling

AR Fetoni, F Paciello, R Rolesi, G Paludetti… - Free Radical Biology and …, 2019 - Elsevier
Hearing loss caused by exposure to recreational and occupational noise remains a
worldwide disabling condition and dysregulation of redox homeostasis is the hallmark of …

Mechanisms of hair cell damage and repair

EL Wagner, JB Shin - Trends in neurosciences, 2019 - cell.com
Sensory hair cells of the inner ear are exposed to continuous mechanical stress, causing
damage over time. The maintenance of hair cells is further challenged by damage from a …

Inner hair cell loss disrupts hearing and cochlear function leading to sensory deprivation and enhanced central auditory gain

R Salvi, W Sun, D Ding, GD Chen… - Frontiers in …, 2017 - frontiersin.org
There are three times as many outer hair cells (OHC) as inner hair cells (IHC), yet IHC
transmit virtually all acoustic information to the brain as they synapse with 90–95% of type I …

Effects of lifetime noise exposure on the middle-age human auditory brainstem response, tinnitus and speech-in-noise intelligibility

JT Valderrama, EF Beach, I Yeend, M Sharma… - Hearing research, 2018 - Elsevier
Recent animal studies have shown that the synapses between inner hair cells and the
dendrites of the spiral ganglion cells they innervate are the elements in the cochlea most …

[PDF][PDF] Noise exposures causing hearing loss generate proteotoxic stress and activate the proteostasis network

N Jongkamonwiwat, MA Ramirez, S Edassery… - Cell reports, 2020 - cell.com
Exposure to excessive sound causes noise-induced hearing loss through complex
mechanisms and represents a common and unmet neurological condition. We investigate …

Altered auditory processing, filtering, and reactivity in the Cntnap2 knock-out rat model for neurodevelopmental disorders

KE Scott, AL Schormans, KY Pacoli… - Journal of …, 2018 - Soc Neuroscience
Sensory processing, and auditory processing in particular, is altered in individuals with
neurodevelopmental disorders such as autism spectrum disorders (ASDs). The typical …

Drug development for noise-induced hearing loss

I Varela-Nieto, S Murillo-Cuesta, M Calvino… - Expert opinion on …, 2020 - Taylor & Francis
Introduction Excessive exposure to noise is a common occurrence that contributes to
approximately 50% of the non-genetic hearing loss cases. Researchers need to develop …