Recent animal studies have shown that the synapses between inner hair cells and the
dendrites of the spiral ganglion cells they innervate are the elements in the cochlea most …

Exposure to excessive sound causes noise-induced hearing loss through complex
mechanisms and represents a common and unmet neurological condition. We investigate …

Sensory processing, and auditory processing in particular, is altered in individuals with
neurodevelopmental disorders such as autism spectrum disorders (ASDs). The typical …

Evidence suggests that damage to the ribbon synapses (RS) may be the main cause of
auditory dysfunction in noise-induced hearing loss (NIHL). Oxidative stress is implicated in …

Introduction Excessive exposure to noise is a common occurrence that contributes to
approximately 50% of the non-genetic hearing loss cases. Researchers need to develop …

The auditory system is particularly vulnerable to blast injury due to the ear's role as a highly
sensitive pressure transducer. Over the past several decades, studies have used a variety of …

Noise-induced hidden hearing loss (NIHHL) has attracted great attention in hearing
research and clinical audiology since the discovery of significant noise-induced synaptic …

Objective Nicotinamide riboside (NR) has been proved to protect the hearing. To achieve
animal models of temporary threshold shift (TTS) and permanent threshold shift (PTS) …

In medicine, biomarkers are a metric for disease state. More generally, a biomarker is
anything that can be used as an indicator for a particular disease state or any physiological …

Importance It is important to determine what frequencies and auditory perceptual measures
are the most sensitive early indicators of noise-induced hearing impairment. Objectives To …