“We've got to get out”—Strategies of human pathogenic fungi to escape from phagocytes
J Sonnberger, L Kasper, T Lange… - Molecular …, 2024 - Wiley Online Library
Human fungal pathogens are a deadly and underappreciated risk to global health that most
severely affect immunocompromised individuals. A virulence attribute shared by some of the …
severely affect immunocompromised individuals. A virulence attribute shared by some of the …
Inbred Mouse Models in Cryptococcus neoformans Research
M Ding, K Nielsen - Journal of Fungi, 2024 - mdpi.com
Animal models are frequently used as surrogates to understand human disease. In the
fungal pathogen Cryptococcus species complex, several variations of a mouse model of …
fungal pathogen Cryptococcus species complex, several variations of a mouse model of …
Differential and cooperative effects of IL-25 and IL-33 on T helper cells contribute to cryptococcal virulence and brain infection
A Hansakon, S Jeerawattanawart, P Angkasekwinai - Scientific Reports, 2023 - nature.com
The epithelial cell-derived cytokines IL-33 and IL-25 are important mediators in driving type-
2 inflammation during C. neoformans infection. Nevertheless, the impact of these cytokines …
2 inflammation during C. neoformans infection. Nevertheless, the impact of these cytokines …
Arginase inhibitor reduces fungal dissemination in murine pulmonary cryptococcosis by promoting anti-cryptococcal immunity
A Hansakon, P Angkasekwinai - International Immunopharmacology, 2024 - Elsevier
Elevation of arginase enzyme activity in the lung contributes to the pathogenesis of various
chronic inflammatory diseases and infections. Inhibition of arginase expression and activity …
chronic inflammatory diseases and infections. Inhibition of arginase expression and activity …
Metabolic regulation of the host–fungus interaction: from biological principles to therapeutic opportunities
R Silva-Gomes, I Caldeira, R Fernandes, C Cunha… - 2024 - academic.oup.com
Fungal infections present a significant global public health concern, impacting over 1 billion
individuals worldwide and resulting in more than 3 million deaths annually. Despite …
individuals worldwide and resulting in more than 3 million deaths annually. Despite …
Murine Models of Cryptococcus Infection
A Hansakon, P Angkasekwinai - Current Protocols, 2024 - Wiley Online Library
Cryptococcus is recognized as one of the emerging fungal pathogens that have major
impact on diverse populations worldwide. Because of the high mortality rate and limited …
impact on diverse populations worldwide. Because of the high mortality rate and limited …