Morphological Characteristics and Clinical Significance of Different Types of Tumor Vessels in Patients with Stages I‐IIA of Squamous Cervical Cancer
MA Senchukova, EV Makarova, EI Shurygina… - Journal of …, 2020 - Wiley Online Library
The determination of factors associated with progression of cervical cancer is important, both
for a recurrence risk assessment and for determining optimal treatment tactics. Previously …
for a recurrence risk assessment and for determining optimal treatment tactics. Previously …
The emerging roles of the ubiquitination/deubiquitination system in tumor radioresistance regarding DNA damage responses, cell cycle regulation, hypoxic responses …
Radiation therapy is one of the first-line treatments for many cancers, with no less than half
of cancer patients receiving it in the US. Despite the development of innovative and high …
of cancer patients receiving it in the US. Despite the development of innovative and high …
[HTML][HTML] ZBTB7A forms a heterodimer with ZBTB2 and inhibits ZBTB2 homodimerization required for full activation of HIF-1
G Kambe, M Kobayashi, H Ishikita, S Koyasu… - Biochemical and …, 2024 - Elsevier
Abstract Hypoxia-inducible factor 1 (HIF-1), recognized as a master transcription factor for
adaptation to hypoxia, is associated with malignant characteristics and therapy resistance in …
adaptation to hypoxia, is associated with malignant characteristics and therapy resistance in …
DDX5 enhances HIF‐1 activity by promoting the interaction of HIF‐1α with HIF‐1β and recruiting the resulting heterodimer to its target gene loci
Y Shirai, T Suwa, M Kobayashi, S Koyasu… - Biology of the …, 2024 - Wiley Online Library
Abstract Background Information Cancer cells acquire malignant characteristics and therapy
resistance by employing the hypoxia‐inducible factor 1 (HIF‐1)‐dependent adaptive …
resistance by employing the hypoxia‐inducible factor 1 (HIF‐1)‐dependent adaptive …
Abundance of d‐2‐hydroxyglutarate in G2/M is determined by FOXM1 in mutant IDH1‐expressing cells
K Bala Bhaskara Rao, K Katragunta, UM Sarma… - FEBS …, 2019 - Wiley Online Library
Isocitrate dehydrogenases (IDHs) are metabolic enzymes that are mutated in several
cancers, resulting in overproduction of d‐2‐hydroxyglutarate (D‐2HG). However, the …
cancers, resulting in overproduction of d‐2‐hydroxyglutarate (D‐2HG). However, the …
Orchestration of lincRNA-p21 and miR-155 in modulating the adaptive dynamics of HIF-1α
Hypoxia-inducible factor-1 (HIF-1) is the key regulator of cellular adaptive response to
hypoxia. Accumulating evidence shows that HIF-1 induces some non-coding RNAs …
hypoxia. Accumulating evidence shows that HIF-1 induces some non-coding RNAs …
Identification of differential expression genes between volume and pressure overloaded hearts based on bioinformatics analysis
Y Fu, D Zhao, Y Zhou, J Lu, L Kang, X Jiang, R Xu… - Genes, 2022 - mdpi.com
Volume overload (VO) and pressure overload (PO) are two common pathophysiological
conditions associated with cardiac disease. VO, in particular, often occurs in a number of …
conditions associated with cardiac disease. VO, in particular, often occurs in a number of …
Comparative Proteomic Analysis of Rana chensinensis Oviduct
H Su, H Zhang, X Wei, D Pan, L Jing, D Zhao, Y Zhao… - Molecules, 2018 - mdpi.com
As one of most important traditional Chinese medicine resources, the oviduct of female
Rana chensinensis (Chinese brown frog) was widely used in the treatment of asthenia after …
Rana chensinensis (Chinese brown frog) was widely used in the treatment of asthenia after …
2‐Hydoxyglutarate: D/R iving Pathology in g L ioma S
DR Wahl, S Venneti - Brain Pathology, 2015 - Wiley Online Library
Common pathways and mechanisms can be found in both cancers and inborn errors of
metabolism. 2‐Hydroxyglutarate (2‐HG) acidurias and isocitrate dehydrogenase (IDH) 1/2 …
metabolism. 2‐Hydroxyglutarate (2‐HG) acidurias and isocitrate dehydrogenase (IDH) 1/2 …