Objective: To explore the role of pain care nursing in ameliorating psychological burden and
improving the efficacy in combined treatment of radiotherapy and zoledronic acid for bone …

Targeting death receptor‐mediated apoptosis in T‐cell acute lymphoblastic leukemia (T‐
ALL), an aggressive disease with poor prognosis, is hindered by the inherent resistance of …

Radiotherapy (RT) has continued to be one of the major pillars in the treatment of cancer for
several decades. Radiation-induced reactive oxygen species (ROS) are essential to kill …

Mutation or transcriptional up-regulation of isocitrate dehydrogenases 1 and 2 (IDH1 and
IDH2) promotes cancer progression through metabolic reprogramming and epigenetic …

In recent years, chemoimmunotherapy has become effective in some advanced cancers, but
its effect is still limited. Transcriptional upregulation of isocitrate dehydrogenase 3α (IDH3α) …

Artificial selection of modern meat-producing chickens (broilers) for production
characteristics has led to dramatic changes in phenotype, yet the impact of this selection on …

Цель исследования-систематизировать и обобщить современные представления о
роли гипоксии в развитии радиорезистентности злокачественных опухолей. Материал …

The purpose of the study was to systematize and summarize modern ideas about the role of
hypoxia in the development of tumor radioresistance. Material and Methods. PubMed …

Glioblastoma multiforme (GBM) is one of the most lethal tumors known to man. This lethality
is partly attributable to its rapid growth, which creates intratumoral regions scarce of oxygen …

In the post-genome wide association study era, an important objective is developing a more
comprehensive understanding of the biological mechanisms through which genetic variants …