[PDF][PDF] Ocena stężeń potencjalnych biomarkerów: VEGF, HIF 1α i YKL-40 u pacjentów z niedrobnokomórkowym rakiem płuca leczonych operacyjnie

M Rydel - 2020 - scholar.archive.org
Wykaz stosowanych skrótów aFGF-kwasowy czynnik wzrostu fibroblastów (z ang. acidic
Fibroblast Growth Factor) AMD-zwyrodnienie plamki żółtej (z ang. Age Related Macular …

[图书][B] Phenotypic and Genetic Analysis of D-2-Hydroxyglutarate Overproducing Yeast Mutants

S Fiola - 2020 - search.proquest.com
The vast majority of low-grade gliomas (LGGs) carry somatic mutations in isocitrate
dehydrogenase 1 (IDH1) and 2 (IDH2) genes. IDH1 and IDH2 catalyze the oxidative …

In silico analysis of IDH3A gene revealed Novel mutations associated with Retinitis Pigmentosa

TA Mahmoud, AH Abdelmoneim, NS Murshed… - bioRxiv, 2019 - biorxiv.org
Abstract Background Retinitis Pigmentosa (RP) refers to a group of inherited disorders
characterized by the death of photoreceptor cells leading to blindness. The aim of this study …

[PDF][PDF] HIF-1 maintains a functional relationship between pancreatic

T Katagiri - pan - pdfs.semanticscholar.org
Hypoxic and stroma-rich microenvironments, characteristic features of pancreatic cancers,
are strongly associated with a poor prognosis. However, whether and how hypoxia …

[PDF][PDF] Regulatory mechanisms of tumor initiation, growth and invasion: the function of isocitrate dehydrogenase 1, acidosis and ephrinB2

N Böğürcü-Seidel - 2018 - d-nb.info
I declare that I have completed this dissertation single-handedly without the unauthorized
help of a second party and only with the assistance acknowledged therein. I have …

[图书][B] Investigating the Genetic Influences of the Germline and Somatic Genomes in Three Subtypes of Lung Cancer

TD O'Brien - 2017 - search.proquest.com
Cancer is a disease of uncontrolled cellular growth. In the late stage, cancer cells may break
the normal boundaries of their given cell type and invade surrounding tissue in a process …

[PDF][PDF] A Metabolomic Investigation of Rho-ROCK Signalling in Metastatic Melanoma

T Kanno, V Sanz-Moreno - 2017 - kclpure.kcl.ac.uk
Metastatic spread is the cause of 90% of cancer-related deaths. Melanoma cells with high
actomyosin contractility, driven by high Rho-Rho Kinase (ROCK) signalling, exhibit a …

Unraveling Cancer Metabolism Through Flux Analysis and Metabolic Engineering

LC Tavares - 2015 - search.proquest.com
Cancer therapies have significantly improved over the last decades. However, some
cancers, such as lung cancer, still have very poor outcomes and high mortality rates, even …

[PDF][PDF] 乳癌でのイソクエン酸脱水素酵素(IDH) アイソフォームの免疫局在: IDH2 は増殖に関係し予後不良因子となる

峯村洋行 - 2021 - tohoku.repo.nii.ac.jp
背景 3. 目的 4. 材料および方法 4-1. 患者検体 4-2. 免疫組織化学 4-3. 免疫染色の評価方法 4-4.
培養細胞 4-5. 細胞株への siRNA 導入 4-6. リアルタイム PCR 4-7. ウェスタンブロッティング 4-8 …

[PDF][PDF] 87. がんの悪性進展促進因子に対するペプチド創薬

原田浩 - 2020 - ueharazaidan.or.jp
がんは 1981 年から我が国の死亡原因の第 1 位で, 国民の健康福祉の向上を目指す上で超える
べき障壁である. がんを克服するためには, がんが発生し, 悪性進展する分子メカニズムを明らかに …