Polymer-based local antibiotic delivery for prevention of polymicrobial infection in contaminated mandibular implants

SR Shah, AM Tatara, J Lam, S Lu… - ACS Biomaterials …, 2016 - ACS Publications
Antibiotic-releasing porous poly (methyl methacrylate)(PMMA) space maintainers,
comprising PMMA with an aqueous porogen and a poly (DL-lactic-co-glycolic acid)(PLGA) …

[HTML][HTML] Are critical size bone notch defects possible in the rabbit mandible?

PL Carlisle, T Guda, DT Silliman… - Journal of the …, 2019 - synapse.koreamed.org
Objectives Small animal maxillofacial models, such as non-segmental critical size defects
(CSDs) in the rabbit mandible, need to be standardized for use as preclinical models of …

Development and characterization of a rabbit model of compromised maxillofacial wound healing

SL Piotrowski, L Wilson, N Dharmaraj… - … Engineering Part C …, 2019 - liebertpub.com
Background: Tissue engineering technologies aiming to enhance maxillofacial wound
healing are often tested in vivo in preclinical models that do not necessarily reflect the …

Interim reconstruction and space maintenance of mandibular continuity defects preceding definitive osseous reconstruction

C Ferretti, E Rikhotso, E Muthray, J Reyneke - British Journal of Oral and …, 2013 - Elsevier
The use of space maintenance in mandibular defects as an interim measure before
definitive osseous reconstruction may prevent problems associated with delayed …

In situ formation of porous space maintainers in a composite tissue defect

PP Spicer, JD Kretlow, AM Henslee… - … Research Part A, 2012 - Wiley Online Library
Reconstruction of composite defects involving bone and soft tissue presents a significant
clinical challenge. In the craniofacial complex, reconstruction of the soft and hard tissues is …

Use of porous space maintainers in staged mandibular reconstruction

AM Henslee, PP Spicer, SR Shah… - Oral and …, 2014 - oralmaxsurgery.theclinics.com
Continuity defects of the mandible can be the result of tumor resection or trauma. In cases
involving high-velocity projectiles, blast injuries, or locally aggressive tumors, bone loss is …

A rapid, flexible method for incorporating controlled antibiotic release into porous polymethylmethacrylate space maintainers for craniofacial reconstruction

PM Mountziaris, SR Shah, J Lam, GN Bennett… - Biomaterials …, 2016 - pubs.rsc.org
Severe injuries in the craniofacial complex, resulting from trauma or pathology, present
several challenges to functional and aesthetic reconstruction. The anatomy and position of …

Degradable, antibiotic releasing poly (propylene fumarate)‐based constructs for craniofacial space maintenance applications

AM Henslee, SR Shah, ME Wong… - … Research Part A, 2015 - Wiley Online Library
Abstract Space maintainers (SMs) used for craniofacial reconstruction function to preserve
the void space created upon bone loss and promote soft tissue healing over the defect …

Tissue engineering in oral and maxillofacial surgery

P Spicer, S Young, FK Kasper, KA Athanasiou… - Principles of Tissue …, 2014 - Elsevier
The oral and maxillofacial region is a highly complex area composed of multiple tissue types
including the facial bones, special sense organs, lining and covering tissues, a rich neural …

Tissue engineering in oral and maxillofacial surgery

S Young, FK Kasper, J Melville, R Donahue… - Principles of Tissue …, 2020 - Elsevier
The oral and maxillofacial region is a highly complex area composed of multiple tissue
types, including the facial bones, special sense organs, lining and covering tissues, a rich …