The effect of antidepressants on the severity of COVID-19 in hospitalized patients: A systematic review and meta-analysis

H Nakhaee, M Zangiabadian, R Bayati, M Rahmanian… - PLoS …, 2022 - journals.plos.org
Introduction Clinical Depression and the subsequent low immunity is a comorbidity that can
act as a risk factor for the severity of COVID-19 cases. Antidepressants such as Selective …

Antidepressant drugs and COVID-19: A review of basic and clinical evidence

M Mas, JA García-Vicente, A Estrada-Gelonch… - Journal of clinical …, 2022 - mdpi.com
The COVID-19 pandemic has encouraged the repurposing of existing drugs as a shorter
development strategy in order to support clinicians with this difficult therapeutic dilemma …

[HTML][HTML] COVID-19 mortality among selective serotonin reuptake inhibitor users—results from a nationwide cohort

MA Stauning, DJ Gür, C Torp-Pedersen… - Clinical Microbiology and …, 2023 - Elsevier
Objective To examine differences in mortality and/or severe acute respiratory syndrome
between selective serotonin reuptake inhibitor-(SSRI) users and non-SSRI users up to 60 …

[HTML][HTML] Repurposing selective serotonin reuptake inhibitors for severity of COVID-19: a population-based study

I Visos-Varela, M Zapata-Cachafeiro… - European …, 2023 - Elsevier
Abstract The World Health Organization has proposed that a search be made for alternatives
to vaccines for the prevention and treatment of COVID-19, with one such alternative being …

The effect of selective serotonin and norepinephrine reuptake inhibitors on clinical outcome of COVID‐19 patients: A systematic review and meta‐analysis

D Firouzabadi, F Kheshti, S Abdollahifard… - Health Science …, 2022 - Wiley Online Library
Abstract Background and Aim Due to the high social and economic burden and also
mortality and morbidity caused by coronavirus disease 2019 (COVID‐19) in the past few …

Prescription of selective serotonin reuptake inhibitors in COVID-19 infection needs caution

MM Borovcanin, K Vesic, YH Balcioglu… - Frontiers in …, 2022 - frontiersin.org
Although Coronavirus disease (COVID-19) infection is primarily associated with fever,
respiratory symptoms, pneumonia, and acute respiratory distress syndrome, the virus …

Difficulty in Repurposing Selective Serotonin Reuptake Inhibitors and Other Antidepressants with Functional Inhibition of Acid Sphingomyelinase in COVID-19 …

P Le Corre, G Loas - Frontiers in Pharmacology, 2022 - frontiersin.org
The rapid spread of COVID-19 has become a health emergency causing an urgent need for
drug treatments to control the outbreak, especially in more vulnerable individuals. This is …

Acid sphingomyelinase (ASM) and COVID‐19: A review of the potential use of ASM inhibitors against SARS‐CoV‐2

PJT Pauletto, CP Delgado… - Cell Biochemistry and …, 2023 - Wiley Online Library
In the last 2 years, different pharmacological agents have been indicated as potential
inhibitors of SARS‐CoV‐2 in vitro. Specifically, drugs termed as functional inhibitors of acid …

In silico analysis of the antidepressant fluoxetine and related drugs at SARS-CoV-2 main protease (Mpro) and papain-like protease (PLpro)

PJ Tronco Pauletto, FB Omage… - Current Drug …, 2023 - ingentaconnect.com
Background: SARS-CoV-2 main protease (Mpro or 3CLpro) and papain-like protease
(PLpro) are common viral targets for repurposed drugs to combat COVID-19 disease …

Association Between Selective Serotonin Reuptake Inhibitors Prevalent Use and COVID-19–Related Mortality: A Retrospective Cohort Study

PI Osores, MN Vivacqua, C Vazquez… - Journal of clinical …, 2023 - journals.lww.com
2019 (COVID-19), many efforts have been made to prevent and to treat the disease. In this
line, the anti-inflammatory effect of selective serotonin reuptake inhibitors (SSRI) as …