Pediatric acute myeloid leukemia is a rare and heterogeneous disease in relation to
morphology, immunophenotyping, germline and somatic cytogenetic and genetic …

Introduction: Trisomy 8 is one of the most common cytogenetic alterations in acute myeloid
leukemia (AML), with a frequency between 10% and 15%. Areas covered: The authors …

The incidence, risk factors, and prognostic significance of extramedullary involvement (EMI)
in adult patients with acute myeloid leukemia (AML) have not been established yet. This …

Acute myeloid leukemia (AML) is the second most common hematologic malignancy in
children. The incidence of childhood AML is much lower than acute lymphoblastic leukemia …

The prognosis of pediatric acute myeloid leukemia (AML) has improved via stratification
therapy. However, relapse or death occurs in 30%–40% of cases. Novel genetic factors for …

Although the outcome has improved over the past decades, due to improved supportive
care, a better understanding of risk factors, and intensified chemotherapy, pediatric acute …

In acute myeloid leukemia (AML), MLL (KMT2A) rearrangements are among the most
frequent chromosomal abnormalities; however, knowledge of the genetic landscape of MLL …

Background Fanconi anemia (FA) is a rare disease of bone marrow failure. FA patients are
prone to develop myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) …

Introduction The aim of the study was to determine molecular genetic and clinical
characterization of acute myeloid leukemia (AML) with trisomy 8 as the sole chromosome …

Background and aims: The objectives of this study were to investigate the cyto-molecular
profile and survival of pediatric acute myeloid leukemia (AML). Methods: This prospective …