The health effects of ambient PM2. 5 and potential mechanisms

S Feng, D Gao, F Liao, F Zhou, X Wang - Ecotoxicology and environmental …, 2016 - Elsevier
The impacts of ambient PM 2.5 on public health have become great concerns worldwide,
especially in the developing countries. Epidemiological and toxicological studies have …

Oxidants and the pathogenesis of lung diseases

J Ciencewicki, S Trivedi, SR Kleeberger - Journal of Allergy and Clinical …, 2008 - Elsevier
The increasing number of population-based and epidemiologic associations between
oxidant pollutant exposures and cardiopulmonary disease exacerbation, decrements in …

The innate and adaptive immune response induced by alveolar macrophages exposed to ambient particulate matter

R Miyata, SF van Eeden - Toxicology and applied pharmacology, 2011 - Elsevier
Emerging epidemiological evidence suggests that exposure to particulate matter (PM) air
pollution increases the risk of cardiovascular events but the exact mechanism by which PM …

[HTML][HTML] Fine particulate matter in acute exacerbation of COPD

L Ni, CC Chuang, L Zuo - Frontiers in physiology, 2015 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a common airway disorder. In particular,
acute exacerbations of COPD (AECOPD) can significantly reduce pulmonary function. The …

[HTML][HTML] PM2.5 Exacerbates Oxidative Stress and Inflammatory Response through the Nrf2/NF-κB Signaling Pathway in OVA-Induced Allergic Rhinitis Mouse Model

CH Piao, Y Fan, TV Nguyen, HS Shin, HT Kim… - International Journal of …, 2021 - mdpi.com
Air pollution-related particulate matter (PM) exposure reportedly enhances allergic airway
inflammation. Some studies have shown an association between PM exposure and a risk for …

Airway hyperresponsiveness development and the toxicity of PM2. 5

X Lu, R Li, X Yan - Environmental Science and Pollution Research, 2021 - Springer
Airway hyperresponsiveness (AHR) is characterized by excessive bronchoconstriction in
response to nonspecific stimuli, thereby leading to airway stenosis and increased airway …

Roles of oxidative stress in signaling and inflammation induced by particulate matter

F Mazzoli-Rocha, S Fernandes… - Cell biology and …, 2010 - Springer
This review reports the role of oxidative stress in impairing the function of lung exposed to
particulate matter (PM). PM constitutes a heterogeneous mixture of various types of particles …

Insights in particulate matter‐induced allergic airway inflammation: focus on the epithelium

KC De Grove, S Provoost, GG Brusselle… - Clinical & …, 2018 - Wiley Online Library
Outdoor air pollution is a major environmental health problem throughout the world. In
particular, exposure to particulate matter (PM) has been associated with the development …

Prooxidant and Proinflammatory Potency of Air Pollution Particulate Matter (PM2.5–0.3) Produced in Rural, Urban, or Industrial Surroundings in Human Bronchial …

M Dergham, C Lepers, A Verdin, S Billet… - Chemical research in …, 2012 - ACS Publications
Compelling evidence indicates that exposure to air pollution particulate matter (PM) affects
human health. However, how PM composition interacts with PM-size to cause adverse …

Fine particulate matter air pollution and atherosclerosis: mechanistic insights

Y Bai, Q Sun - Biochimica et Biophysica Acta (BBA)-General Subjects, 2016 - Elsevier
Background Atherosclerosis is a progressive disease characterized by the accumulation of
lipids and fibrous plaque in the arteries. Its etiology is very complicated and its risk factors …