Associations of combined genetic and lifestyle risks with incident cardiovascular disease and diabetes in the UK Biobank Study

MA Said, N Verweij, P van der Harst - JAMA cardiology, 2018 - jamanetwork.com
Importance Genetic and lifestyle factors both contribute to the risk of developing
cardiovascular disease, but whether poor health behaviors are associated with similar …

Anti-diabetic drugs and weight loss in patients with type 2 diabetes

E Lazzaroni, MB Nasr, C Loretelli, I Pastore… - Pharmacological …, 2021 - Elsevier
Introduction Obesity is frequently a comorbidity of type 2 diabetes. Even modest weight loss
can significantly improve glucose homeostasis and lessen cardiometabolic risk factors in …

Diabetes, obesity, and cancer—pathophysiology and clinical implications

IC Lega, LL Lipscombe - Endocrine reviews, 2020 - academic.oup.com
Obesity and diabetes have both been associated with an increased risk of cancer. In the
face of increasing obesity and diabetes rates worldwide, this is a worrying trend for cancer …

Ischaemic stroke in young adults: a global perspective

E Boot, MS Ekker, J Putaala, S Kittner… - Journal of Neurology …, 2020 - jnnp.bmj.com
Ischaemic stroke at young age is an increasing problem in both developing and developed
countries due to rising incidence, high morbidity and mortality and long-term psychological …

[HTML][HTML] Plant-based diets for personal, population, and planetary health

EC Hemler, FB Hu - Advances in Nutrition, 2019 - Elsevier
Worldwide, the burden of morbidity and mortality from diet-related chronic diseases is
increasing, driven by poor diet quality and overconsumption of calories. At the same time …

[HTML][HTML] Vital signs: recent trends in stroke death rates—United States, 2000–2015

Q Yang - MMWR. Morbidity and mortality weekly report, 2017 - cdc.gov
Introduction: The prominent decline in US stroke death rates observed for more than 4
decades has slowed in recent years. CDC examined trends and patterns in recent stroke …

[HTML][HTML] Dynamics of diabetes and obesity: Epidemiological perspective

A Boles, R Kandimalla, PH Reddy - … Acta (BBA)-Molecular Basis of Disease, 2017 - Elsevier
The purpose of this review article is to understand the current literature on obesity, diabetes
and therapeutic avenues across the world. Diabetes is a chronic lifestyle condition that …

[HTML][HTML] Exosomes in atherosclerosis: performers, bystanders, biomarkers, and therapeutic targets

C Wang, Z Li, Y Liu, L Yuan - Theranostics, 2021 - ncbi.nlm.nih.gov
Exosomes are nanosized lipid vesicles originating from the endosomal system that carry
many macromolecules from their parental cells and play important roles in intercellular …

The metabolic impact of small intestinal nutrient sensing

FA Duca, TMZ Waise, WT Peppler, TKT Lam - Nature communications, 2021 - nature.com
The gastrointestinal tract maintains energy and glucose homeostasis, in part through
nutrient-sensing and subsequent signaling to the brain and other tissues. In this review, we …

The risk of hip and non-vertebral fractures in type 1 and type 2 diabetes: a systematic review and meta-analysis update

T Vilaca, M Schini, S Harnan, A Sutton, E Poku, IE Allen… - Bone, 2020 - Elsevier
Background Diabetes is associated with increased fracture risk but we do not know what
affects this risk. We investigated the risk of hip and non-vertebral fractures in diabetes and …