Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …
Strategies to combat antimicrobial resistance: anti-plasmid and plasmid curing
MMC Buckner, ML Ciusa… - FEMS microbiology …, 2018 - academic.oup.com
Antimicrobial resistance (AMR) is a global problem hindering treatment of bacterial
infections, rendering many aspects of modern medicine less effective. AMR genes (ARGs) …
infections, rendering many aspects of modern medicine less effective. AMR genes (ARGs) …
Plasmid persistence: costs, benefits, and the plasmid paradox
AC Carroll, A Wong - Canadian journal of microbiology, 2018 - cdnsciencepub.com
Plasmids are extrachromosomal DNA elements that can be found throughout bacteria, as
well as in other domains of life. Nonetheless, the evolutionary processes underlying the …
well as in other domains of life. Nonetheless, the evolutionary processes underlying the …
[HTML][HTML] Bacterial cooperation through horizontal gene transfer
Cooperation exists across all scales of biological organization, from genetic elements to
complex human societies. Bacteria cooperate by secreting molecules that benefit all …
complex human societies. Bacteria cooperate by secreting molecules that benefit all …
PLASMe: a tool to identify PLASMid contigs from short-read assemblies using transformer
Plasmids are mobile genetic elements that carry important accessory genes. Cataloging
plasmids is a fundamental step to elucidate their roles in promoting horizontal gene transfer …
plasmids is a fundamental step to elucidate their roles in promoting horizontal gene transfer …
Expanded Diversity and Phylogeny of mer Genes Broadens Mercury Resistance Paradigms and Reveals an Origin for MerA Among Thermophilic Archaea
CA Christakis, T Barkay, ES Boyd - Frontiers in microbiology, 2021 - frontiersin.org
Mercury (Hg) is a highly toxic element due to its high affinity for protein sulfhydryl groups,
which upon binding, can destabilize protein structure and decrease enzyme activity …
which upon binding, can destabilize protein structure and decrease enzyme activity …
Host-specific plasmid evolution explains the variable spread of clinical antibiotic-resistance plasmids
F Benz, AR Hall - Proceedings of the National Academy of …, 2023 - National Acad Sciences
Antibiotic resistance encoded on plasmids is a pressing global health problem. Predicting
which plasmids spread in the long term remains very challenging, even though some key …
which plasmids spread in the long term remains very challenging, even though some key …
Epistatic interactions between the high pathogenicity island and other iron uptake systems shape Escherichia coli extra-intestinal virulence
The intrinsic virulence of extra-intestinal pathogenic Escherichia coli is associated with
numerous chromosomal and/or plasmid-borne genes, encoding diverse functions such as …
numerous chromosomal and/or plasmid-borne genes, encoding diverse functions such as …
Emergence of dominant multidrug-resistant bacterial clades: Lessons from history and whole-genome sequencing
Antibiotic resistance in bacteria has emerged as a global challenge over the past 90 years,
compromising our ability to effectively treat infections. There has been a dramatic increase in …
compromising our ability to effectively treat infections. There has been a dramatic increase in …
[HTML][HTML] Role of Lifestyle Medicine in the Prevention and Treatment of Diseases
M Farrokhi, F Taheri, Z Bayat, M Damiri, M Farrokhi… - Kindle, 2024 - preferpub.org
Lifestyle medicine plays a crucial role in both the prevention and treatment of diseases by
addressing modifiable lifestyle factors that significantly impact health outcomes. This …
addressing modifiable lifestyle factors that significantly impact health outcomes. This …