Background The optimal regional technique to control pain after breast cancer surgery
remains unclear. We sought to synthesize available data from randomized controlled trials …

While many genetic diseases have effective treatments, they frequently progress rapidly to
severe morbidity or mortality if those treatments are not implemented immediately. Since …

Background To summarize recent evidence in terms of health-related quality of life (HRQoL),
functional and oncological outcomes following radical prostatectomy (RP) compared to …

Background Long covid (post covid-19 condition) is a complex condition with diverse
manifestations, uncertain prognosis and wide variation in current approaches to …

Although early studies suggest the Acuity Circles (AC) allocation policy has increased
access to deceased donor liver transplants (DDLTs) for patients with the highest MELD …

Background Conflicting evidence exists regarding the risks and benefits of inotropic
therapies during cardiac surgery, and the extent of variation in clinical practice remains …

Background Pollution is a major threat to global health, and there is growing interest on
strategies to reduce emissions caused by health care systems. Unwarranted clinical …

Background Unwarranted variability in clinical practice is a challenging problem in practice
today, leading to poor outcomes for patients and low-value care for providers, payers, and …

Background Blood pressure (BP) elevations are commonly treated in hospitalized patients;
however, treatment is not guideline directed. Our objective was to assess BP response to …

Background Prescription opioid use has increased steadily in many Western countries over
the past two decades, most notably in the US, Canada, and most European countries …