Psychosis superspectrum I: Nosology, etiology, and lifespan development

KG Jonas, TD Cannon, AR Docherty, D Dwyer… - Molecular …, 2024 - nature.com
This review describes the Hierarchical Taxonomy of Psychopathology (HiTOP) model of
psychosis-related psychopathology, the psychosis superspectrum. The HiTOP psychosis …

The schizophrenia syndrome, circa 2024: What we know and how that informs its nature

R Tandon, H Nasrallah, S Akbarian… - Schizophrenia …, 2024 - Elsevier
With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Examining associations, moderators and mediators between childhood maltreatment, social functioning, and social cognition in psychotic disorders: a systematic …

NE Fares-Otero, L Alameda, MC Pfaltz… - Psychological …, 2023 - cambridge.org
Childhood maltreatment (CM) has been related to social functioning and social cognition
impairment in people with psychotic disorders (PD); however, evidence across different CM …

Can epigenetics shine a light on the biological pathways underlying major mental disorders?

L Alameda, G Trotta, H Quigley, V Rodriguez… - Psychological …, 2022 - cambridge.org
A significant proportion of the global burden of disease can be attributed to mental illness.
Despite important advances in identifying risk factors for mental health conditions, the …

[HTML][HTML] Trauma and psychosis: a qualitative study exploring the perspectives of people with psychosis on the influence of traumatic experiences on psychotic …

C Campodonico, F Varese, K Berry - BMC psychiatry, 2022 - Springer
Background Despite experiencing high rates of trauma and trauma-related conditions,
people with psychosis are seldomly asked about possible traumatic events. While there are …

Trauma-focused therapy in early psychosis: results of a feasibility randomized controlled trial of EMDR for psychosis (EMDRp) in early intervention settings

F Varese, W Sellwood, D Pulford, Y Awenat… - Psychological …, 2024 - cambridge.org
BackgroundTrauma is prevalent amongst early psychosis patients and associated with
adverse outcomes. Past trials of trauma-focused therapy have focused on chronic patients …

[HTML][HTML] The impact of cumulative obstetric complications and childhood trauma on brain volume in young people with psychotic experiences

K Merritt, P Luque Laguna, A Sethi, M Drakesmith… - Molecular …, 2023 - nature.com
Psychotic experiences (PEs) occur in 5–10% of the general population and are associated
with exposure to childhood trauma and obstetric complications. However, the …

Empirically-derived dimensions of childhood adversity and cumulative risk: associations with measures of depression, anxiety, and psychosis-spectrum …

A Gizdic, T Sheinbaum, TR Kwapil… - European journal of …, 2023 - Taylor & Francis
Background: Investigating different approaches to operationalizing childhood adversity and
how they relate to transdiagnostic psychopathology is relevant to advance research on …

[HTML][HTML] Time of exposure to social defeat stress during childhood and adolescence and redox dysregulation on long-lasting behavioral changes, a translational study

M Schnider, R Jenni, J Ramain, S Camporesi… - Translational …, 2022 - nature.com
Traumatic events during childhood/early adolescence can cause long-lasting physiological
and behavioral changes with increasing risk for psychiatric conditions including psychosis …

Exploring the mediation of DNA methylation across the epigenome between childhood adversity and First Episode of Psychosis—findings from the EU-GEI study

L Alameda, Z Liu, PC Sham, M Aas, G Trotta… - Molecular …, 2023 - nature.com
Studies conducted in psychotic disorders have shown that DNA-methylation (DNAm) is
sensitive to the impact of Childhood Adversity (CA). However, whether it mediates the …