Role of β2-adrenergic receptors in chronic obstructive pulmonary disease

A Yang, G Yu, Y Wu, H Wang - Life Sciences, 2021 - Elsevier
Abstract Beta-2 adrenergic receptors (β2-ARs) have important roles in the pathogenesis and
treatment of chronic obstructive pulmonary disease (COPD). In recent years, progress has …

[HTML][HTML] Risk of adverse cardiovascular events with use of inhaled long-acting bronchodilators in management of chronic obstructive pulmonary disease

MT Wang, JH Lai, CL Tsai, JT Liou - journal of food and drug analysis, 2019 - Elsevier
Inhaled long-acting bronchodilators, including long-acting β 2 agonists (LABAs) and long-
acting muscarinic antagonists (LAMAs) are the mainstay therapy in the treatment of chronic …

The evaluation of β-adrenoceptor blocking agents in patients with COPD and congestive heart failure: a nationwide study

KM Liao, TY Lin, YB Huang, CC Kuo… - International journal of …, 2017 - Taylor & Francis
Objective β-Blockers are safe and improve survival in patients with both congestive heart
failure (CHF) and COPD. However, the superiority of different types of β-blockers is still …

Dual versus single long‐acting bronchodilator use could raise acute coronary syndrome risk by over 50%: A population‐based nested case–control study

L Parkin, S Williams, K Sharples… - Journal of internal …, 2021 - Wiley Online Library
Background Coronary heart disease occurs more frequently among patients with chronic
obstructive pulmonary disease (COPD) compared to those without COPD. While some …

Risk of severe cardiovascular events from add-on tiotropium in chronic obstructive pulmonary disease

JT Liou, CW Lin, CL Tsai, YH Wang, JH Lai… - Mayo Clinic …, 2018 - Elsevier
Objective To examine the risk of cardiovascular disease (CVD) from tiotropium added to
inhaled long-acting β 2 agonists (LABAs) and inhaled corticosteroids (ICSs) in a nationwide …

Conventional western treatment combined with Chinese herbal medicine alleviates the progressive risk of lung cancer in patients with chronic obstructive pulmonary …

TH Lin, SI Chen, YC Su, MC Lin, HJ Lin… - Frontiers in …, 2019 - frontiersin.org
Background and purpose: Lung cancer has high global incidence and mortality rates.
Chronic obstructive pulmonary disease (COPD) is strongly associated with lung cancer and …

CD30 is highly expressed in chronic obstructive pulmonary disease and induces the pulmonary vascular remodeling

L Luo, Y Liu, D Chen, F Chen… - BioMed research …, 2018 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is one of the common and underdiagnosed
diseases with the highest morbidity and mortality in the world. The development of COPD …

Use of antipsychotics and the risk of acute respiratory failure among adults: A disease risk score‐matched nested case–control study

MT Wang, CW Lin, CL Tsai, YH Wang… - British journal of …, 2020 - Wiley Online Library
Aims Evidence on acute respiratory failure (ARF) from antipsychotics is scant, and only 1
population‐based study examined this drug safety issue in chronic obstructive pulmonary …

Inhaled therapies for chronic obstructive pulmonary disease: a systematic review and meta-analysis

EL Axson, A Lewis, J Potts, M Pang, S Dickinson… - BMJ open, 2020 - bmjopen.bmj.com
Objectives To integrate evidence from randomised controlled trials (RCTs) and
observational studies on the efficacy of inhaled treatments for chronic obstructive pulmonary …

Research advances in COPD drugs and novel targets

L Wang, C Xiao, Y Liang, Z Weng, W Yang - Nano Life, 2021 - World Scientific
Chronic obstructive pulmonary disease (COPD) is the third-most deadly disease in the world
and will be a major healthcare problem for decades to come. Its etiology is mainly related to …