In an era of proliferating multidrug resistant bacterial infections that are exhausting the
capacity of existing chemical antibiotics and in which the development of new antibiotics is …

The evolutionary arms race between phages and bacteria, where bacteria evolve resistance
to phages and phages retaliate with resistance-countering mutations, is a major driving force …

Infections caused by drug-resistant bacteria, particularly Gram-negative organisms, are
increasingly difficult to treat using antibiotics. A potential alternative is “phage therapy”, in …

At its current rate, the rise of antimicrobial-resistant (AMR) infections is predicted to paralyze
our industries and healthcare facilities while becoming the leading global cause of loss of …

In response to increasing frequencies of antibiotic-resistant pathogens, there has been a
resurrection of interest in the use of bacteriophage to treat bacterial infections: phage …

Antibiotic resistance causes around 700,000 deaths a year worldwide. Without immediate
action, we are fast approaching a post-antibiotic era in which common infections can result …

Bacteriophages have received recent attention for their therapeutic potential to treat
antibiotic-resistant bacterial infections. One particular idea in phage therapy is to use …

Phage therapy is a promising method for the treatment of multidrug-resistant bacterial
infections. However, its long-term efficacy depends on understanding the evolutionary …

We present evidence that phage resistance resulting from overproduction of
exopolysaccharides, mucoidy, provides a general answer to the longstanding question of …

The evolution and spread of antibiotic‐resistant bacteria have renewed interest in phage
therapy, the use of bacterial viruses (phages) to combat bacterial infections. The delivery of …