[HTML][HTML] Embryonic stem cells as tools for in vitro gamete production in livestock

DE Goszczynski, M Navarro, AA Mutto, PJ Ross - animal, 2023 - Elsevier
The goal of in vitro gametogenesis is to reproduce the events of sperm and oocyte
development in the laboratory. Significant advances have been made in the mouse in the …

[HTML][HTML] Application of single-cell RNA sequencing on human testicular samples: a comprehensive review

F Dong, P Ping, Y Ma, XF Chen - International Journal of Biological …, 2023 - ncbi.nlm.nih.gov
So far there has been no comprehensive review using systematic literature search strategies
to show the application of single-cell RNA sequencing (scRNA-seq) in the human testis of …

Single-cell sequencing reveals the reproductive variations between primiparous and multiparous Hu ewes

T Ge, Y Wen, B Li, X Huang, S Jiang… - Journal of Animal Science …, 2023 - Springer
Background In the modern sheep production systems, the reproductive performance of ewes
determines the economic profitability of farming. Revealing the genetic mechanisms …

[HTML][HTML] Single-cell RNA sequencing and UPHLC-MS/MS targeted metabolomics offer new insights into the etiological basis for male cattle-yak sterility

X Wang, J Pei, L Xiong, Y Kang, S Guo, M Cao… - International Journal of …, 2023 - Elsevier
The variety of species can be efficiently increased by interspecific hybridization. However,
because the males in the hybrid progeny are usually sterile, this heterosis cannot be …

Whole genome re-sequencing reveals artificial and natural selection for milk traits in East Friesian sheep

X Li, L Yuan, W Wang, D Zhang, Y Zhao… - Frontiers in Veterinary …, 2022 - frontiersin.org
The East Friesian sheep is one of the important high-yielding dairy sheep breeds, but still
little is known about their genetic and genomic variation during domestication. Therefore, we …

Integrated single cell transcriptome sequencing analysis reveals species‐specific genes and molecular pathways for pig spermiogenesis

YD Zhao, CX Yang, ZQ Du - Reproduction in Domestic Animals, 2023 - Wiley Online Library
Mammalian spermatogenesis is a highly complicated and intricately organized process
involving spermatogonia propagation (mitosis) and meiotic differentiation into mature sperm …

Advances in single-cell transcriptomics in animal research

Y Yan, S Zhu, M Jia, X Chen, W Qi, F Gu… - Journal of Animal …, 2024 - Springer
Understanding biological mechanisms is fundamental for improving animal production and
health to meet the growing demand for high-quality protein. As an emerging biotechnology …

Mechanisms of imbalanced testicular homeostasis in infancy due to aberrant histone acetylation in undifferentiated spermatogonia under different concentrations of Di …

Y Tian, J Guo, L Hua, Y Jiang, W Ge, X Zhang… - Environmental …, 2024 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP), identified as an endocrine-disrupting chemical,
is associated with reproductive toxicity. This association is particularly noteworthy in …

Single-Nucleus RNA-Seq Reveals Spermatogonial Stem Cell Developmental Pattern in Shaziling Pigs

X Tang, C Chen, S Yan, A Yang, Y Deng, B Chen, J Gu - Biomolecules, 2024 - mdpi.com
Normal testicular development ensures the process of spermatogenesis, which is a complex
biological process. The sustained high productivity of spermatogenesis throughout life is …

[HTML][HTML] Single-cell analysis identifies critical regulators of spermatogonial development and differentiation in cattle-yak bulls

YW Zhang, SX Wu, GW Wang, RD Wan… - Journal of Dairy Science, 2024 - Elsevier
Spermatogenesis is a continuous process in which functional sperm are produced through a
series of mitotic and meiotic divisions and morphological changes in germ cells. The …