BACKGROUND The complexity of fertilization failure during assisted reproductive
technologies (ART) is often under-appreciated, as this failure can occur at any number of …

▪ Abstract Many eukaryotic proteins share a sequence designated as the zona pellucida (ZP)
domain. This structural element, present in extracellular proteins from a wide variety of …

The human zona pellucida (ZP) is an extracellular glycoprotein matrix composed of ZP1,
ZP2, ZP3, and ZP4 surrounding the oocyte, and it plays an important role in sperm–egg …

Human zona pellucida (ZP) matrix is composed of four glycoproteins designated as ZP
glycoprotein-1 (ZP1),-2 (ZP2),-3 (ZP3), and-4 (ZP4). Mutations in the genes encoding human …

The zona pellucida is an extracellular matrix consisting of three glycoproteins that surrounds
mammalian eggs and mediates fertilization. The primary structures of mouse ZP1, ZP2, and …

The zona pellucida (ZP) is an extracellular matrix universally surrounding mammalian eggs,
which is essential for oogenesis, fertilization, and pre-implantation embryo development …

Human zona pellucida (ZP) matrix, a delicate network of thin interconnected filaments, is
primarily composed of four glycoproteins, namely, ZP1, ZP2, ZP3, and ZP4. All four zona …

Many secreted eukaryotic glycoproteins that play fundamental roles in development,
hearing, immunity, and cancer polymerize into filaments and extracellular matrices through …

Fertilization is the union of a single sperm and an egg, an event that results in a diploid
embryo. Animals use many mechanisms to achieve this ratio; the most prevalent involves …

The zona pellucida surrounding the egg and pre-implantation embryo is required for in vivo
fertility and early development. Explanatory models of sperm–egg recognition need to take …