Cardiovascular disease among persons living with HIV: new insights into pathogenesis and clinical manifestations in a global context

M Ntsekhe, JV Baker - Circulation, 2023 - Am Heart Assoc
Widespread use of contemporary antiretroviral therapy globally has transformed HIV
disease into a chronic illness associated with excess risk for disorders of the heart and …

[HTML][HTML] Toll-like receptors as pro-thrombotic drivers in viral infections: a narrative review

B Panzer, CW Kopp, C Neumayer, R Koppensteiner… - Cells, 2023 - mdpi.com
Toll-like receptors (TLRs) have a critical role in the pathogenesis and disease course of viral
infections. The induced pro-inflammatory responses result in the disturbance of the …

Cardiovascular dynamics in HIV: the influence of adrenal function and nutritional status

AJ Niwaha, JB Byrd - Circulation Research, 2024 - Am Heart Assoc
This interdisciplinary review explores the intricate nexus between HIV infection, nutrition,
adrenal gland function, and cardiovascular health, highlighting a critical aspect of HIV …

Association of HIV infection and incident abdominal aortic aneurysm among 143 001 veterans

AM Filipkowski, S Kundu, SK Eden, CW Alcorn… - Circulation, 2023 - Am Heart Assoc
Background: People with HIV (PWH) have an increased risk of cardiovascular disease.
Previous cross-sectional data suggest there is a higher prevalence of abdominal aortic …

HIV‐associated infective native aortic aneurysms

A Jönsson, O Ljungquist, K Sörelius - APMIS, 2023 - Wiley Online Library
HIV‐associated infective native aortic aneurysms (INAA) constitute a subcategory of the
disease INAA. This is a very rare group of patients. The aim of this systematic literature …

[HTML][HTML] Gut microbiome and cardiometabolic comorbidities in people living with HIV

M Trøseid, SD Nielsen, I Vujkovic-Cvijin - Microbiome, 2024 - Springer
Background Despite modern antiretroviral therapy (ART), people living with HIV (PLWH)
have increased relative risk of inflammatory-driven comorbidities, including cardiovascular …

Peripheral T-cell activation, Th17 cells, regulatory T-cells, and aortic aneurysm in people with HIV

M Hove-Skovsgaard, J Høgh, MHC Pham, AD Knudsen… - AIDS, 2023 - journals.lww.com
Here, we investigate if peripheral T-cell activation and proportion of Th17 and T-regulatory
cells (Tregs) are associated with aortic aneurysm or aortic diameter in people with HIV. Aorta …

Composite aortic root replacement in African patients with type A aortic dissection: report of 12 cases

CM Mvondo, LCN Yon, HNT Kengni… - Pan African Medical …, 2023 - ajol.info
Type A aortic dissection (TAAD) is associated with high mortality in the absence of
appropriate surgical therapy. The involvement of the aortic root by the intimal tear and the …

Association of HIV serostatus and inflammation with ascending aortic size

AS Minhas, WS Post, B Liu… - Journal of the …, 2022 - Am Heart Assoc
Background The prevalence and extent of subclinical large vessel vasculopathy is not well
defined among people living with HIV. We aimed to evaluate associations between aortic …

[HTML][HTML] Type I interferon receptor subunit 1 deletion attenuates experimental abdominal aortic aneurysm formation

T Shoji, J Guo, Y Ge, Y Li, G Li, T Ikezoe, W Wang… - Biomolecules, 2022 - mdpi.com
Objective: Type I interferon receptor signaling contributes to several autoimmune and
vascular diseases such as lupus, atherosclerosis and stroke. The purpose of this study was …