DNA methylation pathways and their crosstalk with histone methylation

J Du, LM Johnson, SE Jacobsen… - Nature reviews Molecular …, 2015 - nature.com
Methylation of DNA and of histone 3 at Lys 9 (H3K9) are highly correlated with gene
silencing in eukaryotes from fungi to humans. Both of these epigenetic marks need to be …

[HTML][HTML] Dynamic DNA methylation in plant growth and development

A Bartels, Q Han, P Nair, L Stacey, H Gaynier… - International journal of …, 2018 - mdpi.com
DNA methylation is an epigenetic modification required for transposable element (TE)
silencing, genome stability, and genomic imprinting. Although DNA methylation has been …

[HTML][HTML] The hornwort genome and early land plant evolution

J Zhang, XX Fu, RQ Li, X Zhao, Y Liu, MH Li… - Nature plants, 2020 - nature.com
Hornworts, liverworts and mosses are three early diverging clades of land plants, and
together comprise the bryophytes. Here, we report the draft genome sequence of the …

Global increase in DNA methylation during orange fruit development and ripening

H Huang, R Liu, Q Niu, K Tang… - Proceedings of the …, 2019 - National Acad Sciences
DNA methylation is an important epigenetic mark involved in many biological processes.
The genome of the climacteric tomato fruit undergoes a global loss of DNA methylation due …

A DEMETER-like DNA demethylase governs tomato fruit ripening

R Liu, A How-Kit, L Stammitti… - Proceedings of the …, 2015 - National Acad Sciences
In plants, genomic DNA methylation which contributes to development and stress responses
can be actively removed by DEMETER-like DNA demethylases (DMLs). Indeed, in …

Eukaryotic cytosine methyltransferases

MG Goll, TH Bestor - Annu. Rev. Biochem., 2005 - annualreviews.org
▪ Abstract Large-genome eukaryotes use heritable cytosine methylation to silence
promoters, especially those associated with transposons and imprinted genes. Cytosine …

Requirement of CHROMOMETHYLASE3 for Maintenance of CpXpG Methylation

AM Lindroth, X Cao, JP Jackson, D Zilberman… - Science, 2001 - science.org
Epigenetic silenced alleles of the Arabidopsis SUPERMAN locus (the clark kent alleles) are
associated with dense hypermethylation at noncanonical cytosines (CpXpG and asymmetric …

[HTML][HTML] Molecular mechanism of action of plant DRM de novo DNA methyltransferases

X Zhong, J Du, CJ Hale, J Gallego-Bartolome, S Feng… - Cell, 2014 - cell.com
DNA methylation is a conserved epigenetic gene-regulation mechanism. DOMAINS
REARRANGED METHYLTRANSFERASE (DRM) is a key de novo methyltransferase in …

Arabidopsis MET1 Cytosine Methyltransferase Mutants

MW Kankel, DE Ramsey, TL Stokes, SK Flowers… - Genetics, 2003 - academic.oup.com
We describe the isolation and characterization of two missense mutations in the cytosine-
DNA-methyl-transferase gene, MET1, from the flowering plant Arabidopsis thaliana. Both …

Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases

A Jeltsch - Chembiochem, 2002 - Wiley Online Library
DNA methyltransferases catalyze the transfer of a methyl group from S‐adenosyl‐l‐
methionine to cytosine or adenine bases in DNA. These enzymes challenge the …