Alcohol use disorder relapse factors: A systematic review

W Sliedrecht, R de Waart, K Witkiewitz, HG Roozen - Psychiatry Research, 2019 - Elsevier
A relapsing-remitting course is very common in patients with an Alcohol Use Disorder
(AUD). Understanding the determinants associated with alcohol resumption remains a …

[HTML][HTML] Alcohol's effects on the brain: neuroimaging results in humans and animal models

NM Zahr, A Pfefferbaum - Alcohol research: current reviews, 2017 - ncbi.nlm.nih.gov
Brain imaging technology has allowed researchers to conduct rigorous studies of the
dynamic course of alcoholism through periods of drinking, sobriety, and relapse and to gain …

Cortical thickness, surface area, and volume of the brain reward system in alcohol dependence: relationships to relapse and extended abstinence

TC Durazzo, D Tosun, S Buckley… - Alcoholism: Clinical …, 2011 - Wiley Online Library
Background: At least 60% of those treated for an alcohol use disorder will relapse. Empirical
study of the integrity of the brain reward system (BRS) is critical to understanding the …

A roadmap for integrating neuroscience into addiction treatment: a consensus of the neuroscience interest group of the international society of addiction medicine

A Verdejo-Garcia, V Lorenzetti, V Manning… - Frontiers in …, 2019 - frontiersin.org
Although there is general consensus that altered brain structure and function underpins
addictive disorders, clinicians working in addiction treatment rarely incorporate …

Glutamate, GABA, and other cortical metabolite concentrations during early abstinence from alcohol and their associations with neurocognitive changes

A Mon, TC Durazzo, DJ Meyerhoff - Drug and alcohol dependence, 2012 - Elsevier
BACKGROUND: Little is known about the effects of alcohol dependence on cortical
concentrations of glutamate (Glu) or gamma aminobutyric acid (GABA). We used proton …

Predicting relapse after alcohol use disorder treatment in a high-risk cohort: the roles of anhedonia and smoking

LC Nguyen, TC Durazzo, CL Dwyer, AA Rauch… - Journal of psychiatric …, 2020 - Elsevier
On average, two-thirds of individuals treated for alcohol use disorder (AUD) relapse within
six months. There is a critical need to identify modifiable risk factors associated with relapse …

Brain morphology at entry into treatment for alcohol dependence is related to relapse propensity

VA Cardenas, TC Durazzo, S Gazdzinski, A Mon… - Biological …, 2011 - Elsevier
BACKGROUND: We examined whether any differences in brain volumes at entry into
alcohol dependence treatment differentiate subsequent Abstainers from Relapsers …

Increased decision latency in alcohol use disorder reflects altered resting-state synchrony in the anterior salience network

N Canessa, G Basso, I Carne, P Poggi, C Gianelli - Scientific reports, 2021 - nature.com
Increased decision latency in alcohol use disorder (AUD) has been generally explained in
terms of psychomotor slowing. Recent results suggest that AUD patients' slowed decision …

Targeting the salience network: a mini-review on a novel neuromodulation approach for treating alcohol use disorder

CB Padula, LT Tenekedjieva, DM McCalley… - Frontiers in …, 2022 - frontiersin.org
Alcohol use disorder (AUD) continues to be challenging to treat despite the best available
interventions, with two-thirds of individuals going on to relapse by 1 year after treatment …

Brain metabolite alterations related to alcohol use: a meta-analysis of proton magnetic resonance spectroscopy studies

AE Kirkland, BD Browning, RJ Green, L Leggio… - Molecular …, 2022 - nature.com
Alcohol misuse and alcohol use disorder (AlUD) have neurobiological consequences. This
meta-analysis of proton magnetic resonance spectroscopy (MRS) studies aimed to assess …