Intestine is always exposed to external environment and intestinal microorganism; thus it is
more sensitive to dysfunction and dysbiosis, leading to intestinal inflammation, such as …

Colonic epithelial cells are responsible for maintaining a delicate balance between luminal
secretion and the absorption of fluids and ions. This review aims to discuss and update the …

Gastrointestinal diseases are very common problems; available treatments are very limited
and come with a range of side effects. Coumarins are an extensive class of phenolic …

The calcium-sensing receptor (CaSR) plays a pivotal role in systemic calcium metabolism by
regulating parathyroid hormone secretion and urinary calcium excretion. The diseases …

Cyclic nucleotide elevation in intestinal epithelial cells is the key pathology causing
intestinal fluid loss in secretory diarrheas such as cholera. Current secretory diarrhea …

Different from other epithelia, the intestinal epithelium has the complex task of providing a
barrier impeding the entry of toxins, food antigens, and microbes, while at the same time …

Introduction Acute diarrhea often runs a self-limited course and little by way of treatment is
needed except for oral rehydration therapy. Chronic diarrhea poses a longer-term problem …

BACKGROUND (-)-Fenchone is a bicyclic monoterpene present in essential oils of plant
species, such as Foeniculum vulgare and Peumus boldus, used to treatment of …

Pathological new bone formation is a typical pathological feature in ankylosing spondylitis
(AS), and the underlying molecular mechanism remains elusive. Previous studies have …

Initially identified in the parathyroidea, the calcium sensing receptor (CaSR) is now
recognized as an ubiquitously expressed receptor that exerts specific functions in multiple …