Neuromyelitis optica (NMO) is an immune-mediated inflammatory disorder of the central
nervous system. It is characterized by concurrent inflammation and demyelination of the …

Background Neutrophilic asthma is associated with disease severity and corticosteroid
insensitivity. Novel therapies are required to manage this life-threatening asthma phenotype …

Aims. The programmed death‐(PD‐) 1/PD‐1 ligand (PD‐L) pathway plays an important role
in regulating T cell activation and maintaining peripheral tolerance. Accumulated studies …

This study is to investigate the relationship of programmed cell death 1 (PD‐1; also known
as PDCD1) and programmed death‐1‐ligand 1 (PD‐L1; also known as CD274) single …

Objective Allergic asthma is driven by an antigen-specific immune response. This study
aimed to identify immune-related differentially expressed genes in childhood asthma and …

The aim of this study was to explore the impact of polymorphism of PD-1 gene and its
interaction with tea drinking on susceptibility to tuberculosis (TB). A total of 503 patients with …

Antibodies known as 'superagonists', such as those raised against CD28, induce high levels
of signalling activity. Based on the kinetic-segregation model, a hypothesis arose: the …