[HTML][HTML] Radioiodine therapy in advanced differentiated thyroid cancer: Resistance and overcoming strategy

Y Liu, J Wang, X Hu, Z Pan, T Xu, J Xu, L Jiang… - Drug Resistance …, 2023 - Elsevier
Thyroid cancer is the most prevalent endocrine tumor and its incidence is fast-growing
worldwide in recent years. Differentiated thyroid cancer (DTC) is the most common …

Diagnostic and clinical significance of F-18-FDG-PET/CT thyroid incidentalomas

F Bertagna, G Treglia, A Piccardo… - The Journal of Clinical …, 2012 - academic.oup.com
Context: Thyroid incidentaloma diagnosed by 2-[18F]-fluoro-2-deoxy-d-glucose positron
emission tomography/computed tomography (F-18-FDG-PET/CT) is defined as a thyroid …

BRAF Mutation Testing of Thyroid Fine-Needle Aspiration Biopsy Specimens for Preoperative Risk Stratification in Papillary Thyroid Cancer

M Xing, D Clark, H Guan, M Ji, A Dackiw… - Journal of Clinical …, 2009 - ascopubs.org
Purpose This study investigated the utility of BRAF mutation testing of thyroid fine-needle
aspiration biopsy (FNAB) specimens for preoperative risk stratification in papillary thyroid …

Phase II efficacy and pharmacogenomic study of Selumetinib (AZD6244; ARRY-142886) in iodine-131 refractory papillary thyroid carcinoma with or without follicular …

DN Hayes, AS Lucas, T Tanvetyanon… - Clinical Cancer …, 2012 - AACR
Purpose: A multicenter, open-label, phase II trial was conducted to evaluate the efficacy,
safety, and tolerability of selumetinib in iodine-refractory papillary thyroid cancer (IRPTC) …

Molecular pathology of thyroid cancer: diagnostic and clinical implications

JA Fagin, N Mitsiades - Best practice & research Clinical endocrinology & …, 2008 - Elsevier
There is now a reasonably good understanding of the key oncogenic events involved in the
initiation and progression of thyroid cancer. Many of these are characteristic of certain tumor …

BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications

KT Tang, CH Lee - Journal of the chinese medical association, 2010 - journals.lww.com
Papillary thyroid cancer (PTC) is the most common endocrine malignancy, accounting for 85–
90% of all thyroid cancers. Genetic alternations involving the mitogen-activated protein …

[HTML][HTML] PET/CT in the management of differentiated thyroid cancer

E Zampella, M Klain, L Pace, A Cuocolo - Diagnostic and Interventional …, 2021 - Elsevier
The standard treatment of differentiated thyroid cancer (DTC) consists of surgery followed by
iodine-131 (131 I) administration. Although the majority of DTC has a very good prognosis …

Management of recurrent/persistent nodal disease in patients with differentiated thyroid cancer: a critical review of the risks and benefits of surgical intervention versus …

RP Tufano, G Clayman, KS Heller, WB Inabnet… - Thyroid, 2015 - liebertpub.com
Background: The primary goals of this interdisciplinary consensus statement are to define
the eligibility criteria for management of recurrent and persistent cervical nodal disease in …

Radioiodine scintigraphy with SPECT/CT: an important diagnostic tool for thyroid cancer staging and risk stratification

AM Avram - Journal of nuclear medicine technology, 2014 - Soc Nuclear Med
Staging and risk stratification predicate the postoperative management of thyroid cancer
patients, determining not only the need for 131I therapy or alternative options (conservative …

An update on molecular biology of thyroid cancers

O Omur, Y Baran - Critical reviews in oncology/hematology, 2014 - Elsevier
Differentiated thyroid cancer (DTC) is the most common endocrinological malignancy. There
are several histological variants such as papillary and follicular thyroid carcinoma. Many …