BRAF mutations in papillary thyroid carcinoma and emerging targeted therapies

GC Leonardi, S Candido… - Molecular …, 2012 - spandidos-publications.com
Papillary thyroid carcinoma (PTC) is the most common histotype among the thyroid cancer
types. Although PTC is a curable malignancy, many patients relapse after treatment. Thus …

Clinical impact of the detection of BRAF mutations in thyroid pathology: potential usefulness as diagnostic, prognostic and theragnostic applications

S Lassalle, V Hofman, M Ilie, C Butori… - Current medicinal …, 2010 - ingentaconnect.com
A BRAF somatic mutation at residue 600 of the BRAF protein (BRAFV600E) is highly
prevalent in papillary thyroid carcinomas (PTC). This mutation occurs in approximately …

Prognostic role of 18F-FDG PET/CT in the postoperative evaluation of differentiated thyroid cancer patients

L Pace, M Klain, B Salvatore, E Nicolai… - Clinical Nuclear …, 2015 - journals.lww.com
Purpose The aim of this study was to evaluate the role of 18 F-FDG PET/CT performed after
surgery but before radioiodine therapy in patients with differentiated thyroid cancer …

[HTML][HTML] Telomerase reverse transcriptase induced thyroid carcinoma cell proliferation through PTEN/AKT signaling pathway

H Zhang, N Hu - Molecular medicine reports, 2018 - spandidos-publications.com
Thyroid carcinoma is the most common endocrine malignant tumor in the world, and so,
there is a requirement to develop novel molecular targets for thyroid cancer diagnosis and …

The purine receptor P2X7R regulates the release of pro-inflammatory cytokines in human craniopharyngioma

J Nie, G Huang, SZ Deng, Y Bao… - Endocrine-Related …, 2017 - erc.bioscientifica.com
Craniopharyngiomas (CPs) are usually benign, non-metastasizing embryonic malformations
originating from the sellar area. They are, however, locally invasive and generate adherent …

Comparison of diagnostic and prognostic capabilities of 18F-FDG-PET/CT, 131I-scintigraphy, and diffusion-weighted magnetic resonance imaging for postoperative …

S Nagamachi, H Wakamatsu, S Kiyohara… - Japanese journal of …, 2011 - Springer
Purpose The first aim of this study was to compare the detectability of metastasis of
postoperative differentiated thyroid cancer (DTC) among 131 I whole body scintigraphy …

Recent advances in molecular diagnosis of thyroid cancer

I Legakis, K Syrigos - Journal of thyroid research, 2011 - Wiley Online Library
Recent molecular studies have described a number of abnormalities associated with the
progression and dedifferentiation of thyroid carcinoma. These distinct molecular events are …

Evaluation of PTEN, PI3K, MTOR, and KRAS expression and their clinical and prognostic relevance to differentiated thyroid carcinoma

BB Duman, OI Kara, A Uğuz, BT Ates - Contemporary Oncology …, 2014 - termedia.pl
Results: A significant correlation was found between p85 expression and lymphovascular
invasions and between PTEN expression and multifocality (p= 0.048 and p= 0.04 …

Comparison of the diagnostic and prognostic values of 99mTc-MDP-planar bone scintigraphy, 131I-SPECT/CT and 18F-FDG-PET/CT for the detection of bone …

ZL Qiu, YL Xue, HJ Song, QY Luo - Nuclear medicine …, 2012 - journals.lww.com
Objective The aim of this study was to compare the diagnostic and prognostic values of 99m
Tc-MDP-planar bone scintigraphy (99m Tc-MDP-BS), 131 I single-photon emission …

Overexpression of miR-375 and L-type amino acid Transporter 1 in pheochromocytoma and their molecular and functional implications

J Manso, L Bertazza, S Barollo, A Mondin… - International Journal of …, 2022 - mdpi.com
Pheochromocytoma (Pheo) is a tumor derived from chromaffin cells. It can be studied using
18F-dihydroxyphenylalanine (DOPA)—positron emission tomography (PET) due to its …